Peer attachment formation by systemic redox regulation with social training after a sensitive period

Abstract

Attachment formation is the most pivotal factor for humans and animals in the growth and development of social relationships. However, the developmental processes of attachment formation mediated by sensory-motor, emotional, and cognitive integration remain obscure. Here we developed an animal model to understand the types of social interactions that lead to peer-social attachment formation. We found that the social interaction in a sensitive period was essential to stabilise or overwrite the initially imprinted peer affiliation state and that synchronised behaviour with others based on common motivations could be a driver of peer social attachment formation. Furthermore, feeding experience with supplementation of ubiquinol conferred peer social attachment formation even after the sensitive period. Surprisingly, the experience of feeding beyond the cage window was also effective to reduce the required amount ubiquinol, suggesting that peri-personal space modulation may affect socio-emotional cognition and there by lead to attachment formation.

Improving treatment of neurodevelopmental disorders: recommendations based on preclinical studies

“…In adult zebrafish, group behavior (shoaling) can be a useful model of ASD 49 , whereas hyperlocomotion, impulsive swimming and inattention in both larval and adult zebrafish can be relevant to ADHD 50,51 . Chicks (Gallus gallus) also display robust social and locomotor phenotypes, recapitulating several NDD symptoms, including social deficits, accompanied by aberrant brain growth 52 and affective behaviors 53,54 . Likewise, non-human primates, such as common marmosets (Callithrix jacchus), represent another useful model organism with robust social and affective behaviors 55,56 highly sensitive to environmental manipulations that cause NDD-like phenotypes (e.g., ASD-like social deficits or ADHD-like pathological hyperactivity 56 ).…”

Potential of a smartphone as a stress-free sensor of daily human behaviour

“…In the situation of the current study, it was confirmed that the psychological scores of warmth sensation and work efficiency changed in parallel. These results inferred the possibility that psychological modulation might be represented in these complex behavioural patterns as reported previously [1][2][3][4][5][6][7][8][9][10][11]28] and suggested evaluation in human workers including simple shift, acceleration and several ten-second-order cyclic motion. The current study investigated whether the technology could represent not only the commonality but also the individuality that needs to be recognized in all psychological and psychiatric fields.…”

“…We have employed a multivariate analytic methodology of behavioural http://dx.doi.org/10.1016/j.bbr.2014.06.007 0166-4328/© 2014 Elsevier B.V. All rights reserved. output analysis for quantitative emotional state translation called 'Bouquet', with multiple factors being measured from video images and sounds of humans and model animals [1][2][3][4][5][6][7][8][9][10][11]. Non-contact sensors such as video cameras are suited to psychological detection because they do not introduce artefacts of stress through attachment.…”

Elderly Body Movement Alteration at 2nd Experience of Digital Art Installation with Cognitive and Motivation Scores

“…The plots, variance ellipses and shift vectors allowed us to generalize responses by feature per scene. Our results suggest the importance of intervention technology being designed that utilizes diverse testing to elicit individual variation, as well as the importance of repeat testing to allow understanding of time and conditional shift directions [15,[20][21][22][23][24][25][26].…”

“…It is important to note, however, that throughout the experiment the students attempted to communicate with the participants in a calm and consistent manner. Our study paradigm should be furthermore validated considering behavioral interactions between the participants and caregivers and students [15,[20][21][22][23][24][25][26].…”