2020
DOI: 10.7287/peerj.8196v0.1/reviews/1
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Peer Review #1 of "DNA methylation profiling in recurrent miscarriage (v0.1)"

Abstract: Recurrent miscarriage (RM) is a complex clinical problem. However, specific diagnostic biomarkers and candidate regulatory targets have not yet been identified. To explore RMrelated biological markers and processes, we performed a genome-wide DNA methylation analysis using the Illumina Infinium HumanMethylation450 array platform. Methylation variable positions and differentially methylated regions (DMRs) were selected using the Limma package in R language. Thereafter, gene ontology (GO) enrichment analysis and… Show more

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