2019
DOI: 10.7287/peerj.6629v0.2/reviews/1
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Peer Review #1 of "Evidence for an oncogenic role of HOXC6 in human non-small cell lung cancer (v0.2)"

Abstract: Background: Identification of specific biomarkers is important for the diagnosis and treatment of nonsmall cell lung cancer (NSCLC). HOXC6 is a homeodomain-containing transcription factor that is highly expressed in several human cancers; however, its role in NSCLC remains unknown. Methods: The expression and protein levels of HOXC6 were assessed in NSCLC tissue samples by Quantitative real-time PCR (qRT-PCR) and immunohistochemistry, respectively. HOXC6 was transfected into the NSCLC cell lines A549 and PC9, … Show more

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