Peer Review #1 of "Identification of key miRNAs in the progression of hepatocellular carcinoma using an integrated bioinformatics approach (v0.1)"
Abstract:It has been shown that aberrant expression of microRNAs (miRNAs) and transcriptional factors (TFs) is tightly associated with the development of HCC. Therefore, in order to further understand the pathogenesis of HCC, it is necessary to systematically study the relationship between the expression of miRNAs, TF and genes. In this study, we aim to identify the potential transcriptomic markers of HCC through analyzing common microarray datasets, and further establish the differential co-expression network of miRNA… Show more
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