2020
DOI: 10.7287/peerj.9530v0.1/reviews/3
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Peer Review #3 of "Analysis of prognostic genes in the tumor microenvironment of lung adenocarcinoma (v0.1)"

Abstract: Background: Prognostic genes in the tumor microenvironment play an important role in immune biological processes and the response of cancer to immunotherapy. Thus, we aimed to assess new biomarkers that are associated with immune/stromal cells in lung adenocarcinomas (LUAD) using the ESTIMATE algorithm, which also significantly affects the prognosis of cancer. Methods: The RNA sequencing (RNA-Seq) and clinical data of LUAD were downloaded from the the Cancer Genome Atlas (TCGA). The immune and stromal scores w… Show more

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