2018
DOI: 10.7287/peerj.5099v0.1/reviews/3
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Peer Review #3 of "corseq: fast and efficient identification of favoured codons from next generation sequencing reads (v0.1)"

Abstract: Background:Optimization of transgene expression can be achieved by designing coding sequences with the synonymous codon usage of genes which are highly expressed in the host organism. The identification of the so called "favoured codons" generally requires the access to either the genome or the coding sequences and the availability of expression data. Results:Here we describe corseq, a fast and reliable software for detecting the favoured codons directly from RNAseq data without prior knowledge of genomic sequ… Show more

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