Peliosis hepatis

Dai, Yining; Ren, Ze-Ze; Song, Wenyuan; Huang, Haijun; Yang, Danhong; Wang, Mingshan; Huang, Yicheng; Chen, Mei-Juan; Zhang, Jiajie; Tong, Yongxi; Pan, Hongying

doi:10.1097/md.0000000000006471

Cited by 18 publications

(10 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After selection, 33 articles were reviewed (Fig. 2): 2 case series/original articles 25,26 and 31 case reports, 2,3,5,6,10,11,17,27‐50 for a total of 49 histologically confirmed PH patients (Fig. 2).…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

MRI of Peliosis Hepatis: A Case Series Presentation With a 2022 Systematic Literature Update

Calistri

Nardi

Rastrelli

et al. 2023

Magnetic Resonance Imaging

View full text Add to dashboard Cite

BackgroundPeliosis hepatis (PH) is a rare benign condition, characterized by hepatic sinusoidal dilatation and blood‐filled cystic cavities, often found incidentally, with still challenging diagnosis by imaging due to polymorphic appearance.PurposeBased on a retrospective analysis of our series (12 patients) and systematic literature review (1990–2022), to organize data about PH and identify features to improve characterization.Study TypeRetrospective case series and systematic review.PopulationTwelve patients (mean age 48 years, 55% female) with pathology‐proven PH and 49 patients (mean age 52 years, 67% female) identified in 33 studies from the literature (1990–2022).Field Strength/Sequence1,5‐T; T1‐weighted (T1W), T2‐weighted (T2W), diffusion‐weighted (DW), contrast‐enhanced (CE) T1W imaging.AssessmentWe compared our series and literature data in terms of demographic (gender/age/ethnicity), clinical characteristics (symptoms/physical examination/liver test), associated conditions (malignancies/infectious/hematologic/genetic or chronic disorders/drugs or toxic exposure) percentage. On magnetic resonance imaging lesion numbers/shape/mean maximum diameter/location/mass effect/signal intensity were compared. PH pathological type/proposed imaging diagnosis/patient follow‐up were also considered.Statistical TestsJoanna Briggs Institute (JBI) Critical Appraisal Checklist for Case Reports/Series quality assessment. Intraclass correlation and Cohen's kappa coefficients for levels of inter/intrareader agreement in our experience.ResultsPatients were mainly asymptomatic (92% vs. 70% in our study and literature) with associated conditions (83% vs. 80%). Lesions showed homogeneous T1W‐hypointensity (58% vs. 65%) and T2W‐hyperintensity (58% vs. 66%). Heterogeneous nonspecific (25% vs. 51%), centrifugal (34% vs. 8%), or rim‐like centripetal (25% vs. 23%) patterns of enhancement were most frequent, with hypointensity on the hepatobiliary phase (HBP), without restricted diffusivity. Good inter‐ and intrareader agreement was observed in our experience. Concerning JBI Checklist, 19 out of 31 case reports met at least 7 out of 8 criteria, whereas 2 case series fulfilled 5 and 6 out of 10 items respectively.Data ConclusionA homogeneous, not well‐demarcated T1W‐hypointense and T2W‐hyperintense mass, with heterogeneous nonspecific or rim‐like centripetal or centrifugal pattern of enhancement, and hypointensity on HBP, may be helpful for PH diagnosis. Among associated conditions, malignancies and drug exposures were the most frequent.Level of Evidence4Technical EfficacyStage 2

show abstract

Section: Resultsmentioning

confidence: 99%

“…Italic fonts: literature. Literature data references: T1 2,3,5,6,10,11,25 (3 pts), 26 (9 pts), 27‐31,32 (2 pts), 33‐36,38‐40,44‐47,49 ; T2 2,3,5,6,10,11,17,25 (2 pts), 26 (9 pts), 27‐31,32 (2 pts), 33‐44,46‐49 ; DWI 35,36,38,40‐42,46 …”

Section: Resultsmentioning

confidence: 99%

MRI of Peliosis Hepatis: A Case Series Presentation With a 2022 Systematic Literature Update

Calistri

Nardi

Rastrelli

et al. 2023

Magnetic Resonance Imaging

View full text Add to dashboard Cite

show abstract

“…Therefore, the diagnosis of peliosis hepatis is often difficult and delayed ( 33 ). Laparoscopy is a useful examination to sporadically detect dark-blue or dark-red patchy patterns on the liver surface, which is a characteristic finding of peliosis hepatis ( 34 ). Pathological findings are considered the gold standard for the diagnosis of peliosis hepatis, being histologically characterized by blood-filled cavities.…”

Section: Discussionmentioning

confidence: 99%

Hepatic Angiosarcoma with Peliosis Hepatis

et al. 2023

View full text Add to dashboard Cite

A 59-year-old woman presented to our hospital with liver dysfunction. Imaging revealed multiple lesions in the liver. The patient was diagnosed with peliosis hepatis using percutaneous and laparoscopic biopsies. However, her condition worsened with the appearance of new, obvious mass-forming lesions. Therefore, she underwent a second percutaneous biopsy of these lesions and was diagnosed with hepatic angiosarcoma. Her condition progressed rapidly, and she died two weeks after the diagnosis. Diagnosis of hepatic angiosarcoma in the early stages is difficult. It should be noted that hepatic angiosarcoma may be associated with the development of peliosis hepatis.

show abstract

“…[14] Peliosis hepatis is a rare tumor-like lesion that composed of multiple blood-filled cavities that are difficult to distinguish from other hepatic lesions unless examined by biopsy. [15,16] Imaging characteristic of peliosis hepatis is arterial enhancement without rapid washout, [16] which may be similar to type II (plateau pattern) time-concentration curve in QDSA. In contrast, the HCC tended to show Type III (washout pattern) time-concentration curve.…”

Section: Discussionmentioning

confidence: 99%

Assessment of small hepatocellular carcinoma: perfusion quantification and time-concentration curve evaluation using color-coded and quantitative digital subtraction angiography

et al. 2018

View full text Add to dashboard Cite

To explore the role of quantitative digital subtraction angiography (QDSA) in the diagnosis of small hepatocellular carcinoma (HCC).Between November 2015 and November 2017, all patients who underwent chemoembolization for HCC were retrospectively reviewed. Patients with tumors measuring more than 5 cm or evident post-processing imaging artifacts were excluded. Images were post-processed using the QDSA technique. Regions of interest were manually drawn on proper hepatic artery (as a reference), target HCC and peritumoral liver. Time-concentration curves and flow parameters of the peak ratio, subtracted time-to-peak (TTP), and area under the curve (AUC) ratio was obtained and analyzed.A total of 146 HCCs (mean diameter, 1.6 cm) of 71 cirrhotic patients (54 men, 17 women; mean age, 67.7 years) were enrolled. Compared with liver parenchyma, HCCs showed an increased and more rapid flow (peak ratio, AUC ratio, subtracted TTP, and wash-in slope; all P <.001). Compared with untreated HCCs, chemoembolized HCCs showed a slower flow (subtracted TTP and wash-in slope, P = .004 and .002, respectively). HCCs with a typical enhancement pattern on computed tomography (CT) or magnetic resonance imaging (MRI) had a trend toward Type III (washout pattern) time-concentration curves (P <.001). Chemoembolized HCCs had a trend toward Type II (plateau pattern) time-concentration curves (P = .005).QDSA technology can be used to quantify perfusion measurements of HCC and hepatic parenchyma and to assess perfusion changes after HCC chemoembolization.

show abstract

Peliosis hepatis

Cited by 18 publications

References 16 publications

MRI of Peliosis Hepatis: A Case Series Presentation With a 2022 Systematic Literature Update

MRI of Peliosis Hepatis: A Case Series Presentation With a 2022 Systematic Literature Update

Hepatic Angiosarcoma with Peliosis Hepatis

Assessment of small hepatocellular carcinoma: perfusion quantification and time-concentration curve evaluation using color-coded and quantitative digital subtraction angiography

Contact Info

Product

Resources

About