2022
DOI: 10.1056/nejmicm2114098
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Pellagra

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Cited by 3 publications
(2 citation statements)
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“…Typically, in a chronic course, coarsening, scaling, and hyperpigmentation of the skin are also found, as well as painful fissures on the surfaces of the hands and feet. 2 Histologically, orthohyperkeratosis can be seen initially, with atrophy of the epidermis, flattening of the rete ridges, and dermal fibrosis in the final stage. The exact pathomechanism of photosensitivity remains to be conclusively established.…”
Section: Discussionmentioning
confidence: 99%
“…Typically, in a chronic course, coarsening, scaling, and hyperpigmentation of the skin are also found, as well as painful fissures on the surfaces of the hands and feet. 2 Histologically, orthohyperkeratosis can be seen initially, with atrophy of the epidermis, flattening of the rete ridges, and dermal fibrosis in the final stage. The exact pathomechanism of photosensitivity remains to be conclusively established.…”
Section: Discussionmentioning
confidence: 99%
“…Typischerweise finden sich bei einem chronischen Verlauf ebenso eine Vergröberung, Schuppung und Hyperpigmentierung der Haut sowie schmerzhafte Fissuren an Hand-und Fußflächen. 2 Histologisch bestehen anfangs Orthohyperkeratosen, im Endstadium eine Atrophie der Epidermis, Abflachung der Reteleisten und eine dermale Fibrose. Der genaue Pathomechanismus der Photosensitivität ist nicht endgültig geklärt.…”
Section: Diskussionunclassified