Pellagra: A Clinical, Histopathological, and Epidemiological Study of 7 Cases

Severe pellagra masked by concurrent plaque psoriasis: A case report of a hidden diagnosis

“…Pellagra is more commonly seen in developing countries, but it can also be seen in developed areas in the setting of secondary causes of malnutrition, such as alcoholism [4,5]. Alcoholism is known to interfere with nutrient absorption [4,5], and chronic alcohol consumption can exacerbate existing nutritional deficits.…”

“…Alcoholism is known to interfere with nutrient absorption [4,5], and chronic alcohol consumption can exacerbate existing nutritional deficits.…”

“…There are a variety of biochemical etiologies that lead to photosensitivity in patients with pellagra, one of which is niacin deficiency. The deficiency in cofactors alters the process of skin cellular repair, either by impairing repair of UV damage or decreasing the energy transfer to rapidly turn over skin cells [4,5].…”

“…In the case of pellagra, which also appears as scaly plaques, treatment would be targeted towards dietary supplementation instead. Although uncommon in developed countries, it can be seen in the setting of malnourishment and/or malabsorption [4,5]. Clinical pellagra should be considered as a diagnosis in patients with chronic alcoholism, malnutrition, and amino acid imbalance.…”

Cutaneous manifestations of pellagra in a patient with rheumatoid arthritis

“…2 The disease is common in malnourished individuals, chronic alcoholics, as a complication of isoniazid therapy and food faddists. 3,4 Though the condition is common, diagnosis is often overlooked or delayed resulting in life threatening complications. If pellagra is diagnosed and treated appropriately the prognosis for recovery is excellent.…”