Pelvic Exenteration: An Updated Mini-Review from 1948 to 2020

A Systematic Review on Overall Survival and Disease-Free Survival Following Total Pelvic Exenteration

“…The main indications for PE include primary, recurrence or locally advanced tumors (cervix, rectum, Vulva, bladder) and recurrence after radiotherapy (cervix) and sarcoma (Ethem Unal et al, 2019;PelvExCollaborative, 2019). While distant metastases include involvement of the iliac vessels, pelvic side wall and para-aortic lymphadenopathy, proximal of sacrum bone to S1/S2 or sciatic foramen are contraindications (Ethem Unal et al, 2019).…”

“…Despite the morbidity of more than 50% , the complications of surgery up to 60% and surgical reoperation up to 10% of cases, the number of cases of complete PE is increasing in the world (Lewandowska et al, 2020). Anyway, recent studies tend to more radical surgeries including sidewalls and vessels and perhaps because of this, surgical indications are more common at this time (Ethem Unal et al, 2019;Lewandowska et al, 2020). However, the risk of surgical complications in TPE has been reported to be 31.6-86%.…”