Radical Prostatectomy 2013
DOI: 10.1007/978-1-4614-8693-0_4
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Pelvic Lymph Node Dissection for Prostate Cancer

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Cited by 4 publications
(5 citation statements)
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“…Before performing PLND, it is necessary to routinely use nomograms to predict the extent of lymph node invasion before surgery. According to these nomograms, patients with a serum prostate-specific antigen (PSA) of over 10 ng/mL, a Gleason score of over 6, or a stage T3 tumour (according to the Tumour, Nodes, and Metastases [TNM] staging system) defined by digital rectal examination (DRE), have a 5-65% risk of lymph node involvement [6][7][8]. According to the EAU guidelines, patients with moderate to high risk PCa who have an LNpositive estimated risk of more than 5% should undergo extend pelvic lymph node dissection (ePLND) [9].…”
Section: Introductionmentioning
confidence: 99%
“…Before performing PLND, it is necessary to routinely use nomograms to predict the extent of lymph node invasion before surgery. According to these nomograms, patients with a serum prostate-specific antigen (PSA) of over 10 ng/mL, a Gleason score of over 6, or a stage T3 tumour (according to the Tumour, Nodes, and Metastases [TNM] staging system) defined by digital rectal examination (DRE), have a 5-65% risk of lymph node involvement [6][7][8]. According to the EAU guidelines, patients with moderate to high risk PCa who have an LNpositive estimated risk of more than 5% should undergo extend pelvic lymph node dissection (ePLND) [9].…”
Section: Introductionmentioning
confidence: 99%
“…[TNM] staging system) de ned by digital rectal examination (DRE), have a 5-65% risk of lymph node involvement [6][7][8]. According to the EAU guidelines, patients with moderate to high risk PCa who have an LN-positive estimated risk of more than 5% should undergo extend pelvic lymph node dissection (ePLND) [9].…”
Section: Introductionmentioning
confidence: 99%
“…This, in combination with the availability of nomograms [9] assessing the individual’s risk for node positivity, contributed to the decline of the proportion of patients who receive PLND as well as the extent and yield of PLND [1012]. However, the accurate detection of lymph node metastases remains particularly important for staging purposes [13] since most nomograms may underestimate the true risk of nodal metastasis [1415], and for the therapeutic benefit of PLND.…”
Section: Introductionmentioning
confidence: 99%
“…However, no reliable imaging modality to detect lymph node metastases is currently available [13]. Primarily using size criteria, both computed tomography (CT) and magnetic resonance imaging (MRI) typically lack sensitivity for the detection of metastases of less than one centimeter in size, which are the most common type of metastases occurring in contemporary series [5, 16].…”
Section: Introductionmentioning
confidence: 99%