The Covid-19 pandemic has had an impact on the economies of countries in the world, including Indonesia. The low trade balance, public consumption and the implementation of large-scale social restrictions (PSBB) have caused business actors to suffer losses and even go out of business, especially Micro, Small and Medium Enterprises (MSMEs). Assistance to MSMEs has been provided by the government to maintain the functioning of the economy in the micro environment. However, the provision of this assistance needs to be carried out further analysis because there are reports that the assistance is not on target, causing the budget spent to be ineffective. In this research, an analysis will be carried out on the provision of assistance from the government to MSMEs, especially in Pekalongan district, using data mining techniques, especially classification. The algorithms used are K-Nearest Neighbor (K-NN) and C.45 which are then compared to determine the highest level of effectiveness in recommendations for providing MSME assistance in the District. Pekalongan. The data used was 312 MSMEs and after going through the data preprocessing process we got accurate data, namely 279. The data was divided into 2, namely training data of 200 data and testing data of 79 data. The results of this research, the K-NN algorithm obtained an accuracy level of 94.94%, precision 94.73% and recall 94.73%, while the C.45 algorithm obtained an accuracy level of 86.08%, precision 87.21% and recall 88.3%. Based on the results of this research, it can be concluded that the use of data mining techniques with the K-NN and C4.5 algorithms has a high level of accuracy for recommendations for assistance to MSMEs, however for the best results you can use the K-NN algorithm which has an accuracy level of 94.94%.