2007
DOI: 10.1016/j.tracli.2007.10.003
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Pemphigus and HLA in Morocco

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Cited by 21 publications
(27 citation statements)
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“…However, no association between this allele or any other HLA‐A alleles and PV was found in our study, similar to the study by Brick et al . who did not find any association between HLA‐A antigens and PV.…”
Section: Discussionsupporting
confidence: 91%
“…However, no association between this allele or any other HLA‐A alleles and PV was found in our study, similar to the study by Brick et al . who did not find any association between HLA‐A antigens and PV.…”
Section: Discussionsupporting
confidence: 91%
“…Figure 1 depicts significant associations found across the genome, demonstrating a high concentration of highly associated SNPs near the major histocompatibility complex (MHC) locus. Out of 82 markers that were identified as significantly associated with PV under a controlled false discovery rate of 0.05 (BH), 69 were found to be located on 6p21.3, within the boundaries of the MHC locus (Supplementary Table S1 online), as demonstrated previously in several studies (Miyagawa et al, 2002;Slomov et al, 2003;Brick et al, 2007;Shams et al, 2009;Tunca et al, 2010). The 69 SNPs found on 6p21.3 are distributed within four highly associated peaks 1 6 1 7 1 8 1 9 2 1 2 0 2 2 Figure 1.…”
Section: Genome-wide Association Studysupporting
confidence: 69%
“…HLA-DQA1, HLA-DQB1, and HLA-DRBs loci have been described in association with PV in previous studies in both Jewish and non-Jewish populations (Ahmed et al, 1993;Bordenave et al, 2001;Miyagawa et al, 2002;Slomov et al, 2003;Gazit and Loewenthal, 2004;Tron et al, 2005;Brick et al, 2007;Shams et al, 2009). The other three gene loci have not yet been reported in association with PV but harbor variants predisposing to other inflammatory and/or skin disorders (Simmonds et al, 2006;Fernandez-Morera et al, 2008;Okuyama et al, 2008;Barcellos et al, 2009;Cialfi et al, 2010;Clancy et al, 2010;Hsueh et al, 2010;Jin et al, 2011;Juyal et al, 2011).…”
Section: Genome-wide Association Studymentioning
confidence: 96%
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“…However, there is variation in the dominant clinical phenotype among countries. PV is the commonest subtype in Egypt (Cairo University hospital records), Sudan, Saudi Arabia, Kuwait, Morocco, Syria and Yemen . PV represents 95.4% in Sudan, 72.2% in Kuwait and 94.7% in southern region of Saudi Arabia of the total pemphigus patients.…”
Section: Types Of Pemphigus In the Arab Worldmentioning
confidence: 99%