Pemphigus végétant périanal

Abstract

Acanthose, hyperkératose et spongiose de l'épiderme et infiltrat inflammatoire lympho-plasmocytaire (hématoxyline et éosine, Â 4)

Pemphigus vegetans‐Neumann variant of the vulva

“…Immunosuppressive drugs and dapsone may be associated with good therapeutic response, as in our patient's case. Isolated vulvar and perianal localizations of PV remain unusual and very rarely described in the literature, 2,4 which makes our observation original.…”

“…1 Furthermore, there are some local factors such as microbial colonization and maceration due to the intertriginous localization. 2 Two clinical forms can be distinguished: the Neumann form, in which the initial lesions present as vesicles or bullae evolving to erosions and wet vegetations, and the Hallopeau form, in which vegetative lesions succeed pustules. 3 Lesions are usually found in the folds (inguinal, submammary, axillary, or intergluteal), and the Nikolsky's sign is often positive.…”