Pemphigus vulgaris and pregnancy: Risk factors and recommendations

Goldberg, Neil S.; DeFeo, Charles P.; Kirshenbaum, Nancy

doi:10.1016/0190-9622(93)70123-b

Cited by 69 publications

(51 citation statements)

References 16 publications

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“…4 We do report a case of pemphigus vulgaris with pregnancy. She conceived during the active phase of the disease and treated with steroids throughout pregnancy.…”

Section: Introductionmentioning

confidence: 88%

Pemphigus Vulgaris with Pregnancy

G¹,

Umadevi²,

Padma³

et al. 2012

Journal of South Asian Federation of Obstetrics and Gynaecology

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Pemphigus vulgaris is an autoimmune bullous dermatosis affecting skin and mucous membrane.2 It affects all races and both sexes equally. It is common during the 5th and 6th decade of life.3 It is exceedingly rare in pregnancy 5 and is associated with increased maternal morbidity and poor neonatal outcome. 4 We do report a case of pemphigus vulgaris with pregnancy. She conceived during the active phase of the disease and treated with steroids throughout pregnancy. She delivered a live preterm, appropriate for gestational age and constitutionally small fetus.

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“…4 We do report a case of pemphigus vulgaris with pregnancy. She conceived during the active phase of the disease and treated with steroids throughout pregnancy.…”

Section: Introductionmentioning

confidence: 88%

Pemphigus Vulgaris with Pregnancy

G¹,

Umadevi²,

Padma³

et al. 2012

Journal of South Asian Federation of Obstetrics and Gynaecology

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“…28,29 In a cesarean section, patients who receive long-term steroid therapy will increase the risk of disease itself and corticosteroids may complicate wound healing. Therefore, except for obstetric contraindications, vaginal delivery is recommended.…”

Section: Discussionmentioning

confidence: 99%

Pemphigus vulgaris in pregnancy with transient neonatal pemphigus - can psychological stress be culprit?

Bhagat

Raj

Arora

2017

Int J Reprod Contracept Obstet Gynecol

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Pemphigus vulgaris (PV) is a rare life threatening, autoimmune bullous disease affecting mucous membrane and skin. Pregnancy and emotional stress may be the possible triggering factors for PV. It is a very rare phenomenon with less than 27 cases of pregnancy induced PV and only 9 cases of neonatal pemphigus reported in literature. The lesions may appear transient in neonate which resolve spontaneously over 2-3 weeks. We hereby, report a case of 26-year-old female who developed PV in second trimester of pregnancy with peripartum depression, which was managed by intravenous, oral and topical steroids and selective-serotonin reuptake inhibitor (SSRI). Furthermore, the development of transient neonatal pemphigus raises the possibility of genetic linkage from maternal to fetal transmission.

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“…According to Goldberg vaginal birth can result in worsening and spreading of pemphigus while corticosteroids can delay wound healing in patients undergoing caesarean section. 12 However, caesarean is indicated in patients with pemphigus lesions on genital mucosa. In our patient there was no involvement of genital area whereas skin of lower abdomen was involved making caesarean section a less appropriate mode of delivery.…”

Section: Fig 2 Oral Mucosal Lesion In Pemphigus Vulgarismentioning

confidence: 99%