2023
DOI: 10.1186/s13613-023-01230-w
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Pendelluft in hypoxemic patients resuming spontaneous breathing: proportional modes versus pressure support ventilation

Daniel H. Arellano,
Roberto Brito,
Caio C. A. Morais
et al.

Abstract: Background Internal redistribution of gas, referred to as pendelluft, is a new potential mechanism of effort-dependent lung injury. Neurally-adjusted ventilatory assist (NAVA) and proportional assist ventilation (PAV +) follow the patient’s respiratory effort and improve synchrony compared with pressure support ventilation (PSV). Whether these modes could prevent the development of pendelluft compared with PSV is unknown. We aimed to compare pendelluft magnitude during PAV + and NAVA versus PSV… Show more

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Cited by 5 publications
(2 citation statements)
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“…3 Medical Surgical Neuro ICU, Toronto Western Hospital, University Health Network, Toronto, Canada. 4 Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada. 5 Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, Unity Health Toronto, Toronto, Canada.…”
Section: Fundingmentioning
confidence: 99%
See 1 more Smart Citation
“…3 Medical Surgical Neuro ICU, Toronto Western Hospital, University Health Network, Toronto, Canada. 4 Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada. 5 Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, Unity Health Toronto, Toronto, Canada.…”
Section: Fundingmentioning
confidence: 99%
“…In addition, lung injury and systemic inflammation are primers for P-SILI and myotrauma with excessive concentric or eccentric loading [1,3]. Mechanisms of P-SILI include excessive global and regional lung stress (due to pendelluft) and increased transvascular pressure, and are directly associated with the magnitude and timing of inspiratory effort [3,4]. There is also evidence of interaction between lung and other organs such as brain and kidneys.…”
mentioning
confidence: 99%