Pengaruh Pemberian Ekstrak Daun Jamblang (Egenia cumini Merr.) Terhadap Pertumbuhan Streptococcus pyogenes

Abstract

The flavonoids content of the leaf of Jamblang or Java plum (Egenia cumini Merr.) have the potential to be developed as an anti-microbial agents, especially for Streptococcus pyogenes infections. This research aims to determine the antibacterial activity of Java plum leaf extract (Egenia cumini Merr.) against the growth of Streptococcus pyogenes bacteria. The java plum leaf obtained in the Tamalanrea area of Makassar City was extracted using 96% ethanol by maceration. The dry extract obtained was prepared with concentrations of 2%, 4% and 8% w/v respectively and then tested for anti-bacteria by the agar diffusion method using Nutrient Agar media with a tetracycline comparison. The results showed that the inhibition zone diameter in Java plum Leaf Extract (Egenia cumini Merr.) at a concentration of 2% w/v was 29.0 mm, 4% w/v was 35.0 mm, and 8% w/v was 42.0 mm as well as with Tetracyclines was 78, mm. Therefore, it was concluded that Java plum Leaf Extract (Egenia cumini Merr.) at a concentration of 8% w/v has the greatest antibacterial power (p <0.05), but the effect was smaller compared to Tetracycline (p <0.05).