Oil palm frond is a lignocellulose material, by pyrolysis, it will produce liquid smoke which have many advantages because of the compounds, such as acetic acid, carbonyls and phenolics contained in it. The pyrolysis of oil palm fronds in this study carried out at temperatures 400 °C, 500 °C, and 600 °C for 40 minutes, 90 minutes, and 120 minutes. There were 3 parameters observed in this study, they were acetic acid, phenolics and carbonyl contents which were analyzed by GC-MS instrument. The results of the study showed that the different temperatures and times of pyrolysis affected the content of chemical components in liquid smoke and acetic acid was the most dominant component obtained in the liquid smoke. The highest acetic acid content in the liquid smoke obtained was 92,30% at pyrolysis temperature of 500 °C for 120 minutes. Meanwhile, the highest total phenolic content obtained was 7,32% at pyrolysis temperature of 600 °C for 120 minutes and the highest carbonyl content obtained was 32,56% at the pyrolysis temperature of 400 °C for 60 minutes