Pengaruh Terapi Bekam Basah Dalam Menurunkan Apoliprotein-B Pada Penderita Hiperkolesterolemia

Abstract

Hypercholesterolemia is a high level of cholesterol in the blood. Patients must take anti-cholesterol drugs for a long time, so they are at risk of experiencing side effects from the drug. Apo-B and total cholesterol are indicators of cholesterol levels in the blood. Wet cupping therapy is a method of excreting metabolic waste in the blood through the surface of the skin. The study aims to prove the effect of wet cupping therapy as a complementary therapy to decrease Apolipoprotein-B. Method: This research is Quasy experimental research using humans as research subjects. The dependent variable is Apo-B, and total cholesterol gave wet cupping treatment. Cupping is done twice, 7 points, using a G21 needle. A large sample of 32 people with hypercholesterolemia divided into treatment groups and control groups. The research subjects were selected based on sample inclusion criteria. After 12 hours of fasting and still taking simvastatin, blood was taken through 5ml of the brachial vein. Put into a 2ml purple tube containing EDTA the rest inserted in a red tube. Apo-B measurement using ELISA sandwich method, elabscience reagent, BiopharmaELISA reader tool, in units of ng/ml. Total cholesterol uses the enzymatic colorimetry method, diasys reagent, Biolyzer100 spectrophotometry, in mg/dl units. Data analysis was carried out with the Wilcoxon Signed Ranks Test with a significance level of 5% (α = 0.05), the pre-datacompared with the post data. Results: A significant reduction in Apo-B measurements with p-value 0.000 (α <0.05), SD 42. Conclusion: Intervention of wet cupping therapy can reduce Apo-B levels in the blood. Further research needs to be done to measure the potential for prevention of atherosclerosis.

Literature Review Wet Cupping Technique on Uric Acid Levels in Patients With Hyperuricemia

“…The difference in uric acid levels between stage I and stage II examinations was 1.663 with a standard deviation of 1.458. The results of statistical tests obtained p-value = 0.000, so it can be said that there is a significant difference between uric acid levels in stage I examinations and stage II examinations (Widodo & Mustofa, 2017). Uric acid is a by-product of the body's production, so its presence can be normal in blood and urine.…”

The Combination of Acupressure and Cupping Therapy for Hypertension Patients' Blood Pressure

“…As in the study by Sormin (2019) which proved that there was a difference in blood pressure before and after the intervention (p-value = 0.000), where the average Candrawati & Sukraandini (2021) which showed the benefits of therapy cupping in reducing blood pressure in hypertension sufferers (p-value < 0.05). 10,12,6 Cupping is a therapy by removing metabolic blood containing toxins and oxidants from the body through the surface of the skin.. 13 The effect of cupping can calm the work of the sympathetic nerves and control the amount of the hormone aldosterone in the nervous system, this stimulates the secretion of enzymes which act as angiotensin renin which can reduce blood volume, and produce nitric oxide which functions in vasodilation of blood vessels so that blood pressure decreases. 14 It is hoped that the combination of acupressure and cupping therapy can provide optimal results…”