<p>Technological developments have triggered the emergence of various kinds of learning media innovations. Learning media is a very important part of the learning process. In this study, researchers designed a learning media in the form of a virtual laboratory on the practicum material of the basics of analytical chemistry which is integrated with multi-representation triplets to create and describe the results of learning media.</p>The method used in this development was Research and Development (R&D) method using the 4-D (four-D) development model. Data collection used qualitative and quantitative data. The qualitative data were in the form of comments and suggestions from the validator, while the quantitative data were the validation questionnaire and legibility test. The results showed that the validation of the material obtained a percentage of 84% (very valid), media validation of 78% (valid), and the results of trials on correspondents obtained a percentage in the range 81-92% (very valid). It can be concluded that the virtual laboratory learning media on the analytical chemistry laboratory material with the integration of the developed multi-representation triplet explanations is feasible to use, especially in the practicum of the basics of analytical chemistry on the topic of group I cation analysis and argentometry. This shows that the virtual laboratory developed has the potential to support online practicum learning, and the macroscopic, submicroscopic, and symbolic depiction in the virtual laboratory can help the process of receiving information by students