We complete the calculation of the element $$ {\Gamma}_{12}^q $$
Γ
12
q
of the decay matrix in $$ {B}_q-{\overline{B}}_q $$
B
q
−
B
¯
q
mixing, q = d, s, to order αs in the leading power of the Heavy Quark Expansion. To this end we compute one- and two-loop contributions involving two four-quark penguin operators. Furthermore, we present two-loop QCD corrections involving a chromomagnetic operator and either a current-current or four-quark penguin operator. Such contributions are of order $$ {\alpha}_s^2 $$
α
s
2
, i.e. next-to-next-to-leading-order. We also present one-loop and two-loop results involving two chromomagnetic operators which are formally of next-to-next-to-leading and next-to-next-to-next-to-leading-order, respectively. With our new corrections we obtain the Standard-Model prediction ∆Γs/∆Ms = (5.20 ± 0.69) · 10−3 if $$ {\Gamma}_{12}^s $$
Γ
12
s
is expressed in terms of the $$ \overline{\mathrm{MS}} $$
MS
¯
b-quark mass, while we find ∆Γs/∆Ms = (4.70 ± 0.96) · 10−3 instead for the use of the pole mass.