Penile Gangrene by Calciphylaxis: An Unusual Clinical Presentation in a Patient with Diabetic Nephropathy on Hemodialysis

Penile necrosis by calciphylaxis leading to gangrene in a patient with chronic renal failure on dialysis: A case report

“…In previously reported cases [ [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] ] ( Table 1 ), all patients including the present case had chronic kidney disease (78% were reported on dialysis) and diabetes mellitus which could be a predisposing factor [ 16 ]. Seven reported cases, including our patient’s case, had a high blood pressure and two of them had a long history with smoking [ [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] ]. In our case, other risk factors were found such as obesity and anticoagulant treatment that may worsen pre-existing atherosclerosis.…”

“…In our case, the histopathological diagnosis of calciphylaxis shows diabetic microangiopathy that is accompanied by vascular calcification of both the tunica intima and media of blood vessels with intimal fibroblastic proliferation. In other cases [ [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] ], the histopathological diagnosis was performed in 6 patients including our case and 8 patients who received at least one radiological assessment. In our case, the patient received an arteriography that showed multiple vascular calcifications at the level of the internal iliac artery and its branches.…”

Penile calciphylaxis in a patient with end-stage renal disease: a case report and review of the literature

“…A total of 50 cases of penile calciphylaxis have been reported in the English literature ( Table 1 ) [ 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 ]. The average age was 54.5 years (range 32 to 81).…”

Italian experiences in the management of andrological patients at the time of Coronavirus pandemic

“…In the first 50 days we had to intervene on two traumas of the genital tract that happened due to working activities. We listed criteria to plan andrological surgery in agreement with our experience, the Covid Task Force Unit in our hospital and published Guidelines on urological surgery (17)(18)(19)(20)(21). The andrological surgical activity included two orchiectomies for testicular cancer, one penile amputation with inguinal and ipsilateral pelvic lymph node dissection for penile cancer (Figure 4) and one surgery for severe gangrenous necrotizing fasciitis of the genitals in a 58-year male with diabetes, HIV and drugs addiction.…”