Penile metastases of rectal adenocarcinoma

Peršec, Zoran; Peršec, Jasminka; Sović, Tomislav; Rako, Duje; Savić, Ivan

doi:10.1016/j.jviscsurg.2013.08.009

Cited by 14 publications

(14 citation statements)

References 4 publications

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“…Metastatic involvement of the penis despite its proximity to the rectum mainly originates from the bladder and prostate. Regional lymph nodes, the liver, lungs, and the vertebral column are most likely to be involved in metastasis from rectal cancer [5].…”

Section: Discussionmentioning

confidence: 99%

Penile metastases of rectal adenocarcinoma after abdominoperineal resection: a case report

Marghich¹,

Dkhissi²,

Alila³

et al. 2019

J Med Case Reports

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Background Penile metastases are very rare and arise most frequently from genitourinary cancers. Penile metastases from rectal adenocarcinoma are less common. Case presentation We report the case of a 47-year-old North Afican man with penile metastases from a rectal adenocarcinoma, which was discovered 4 months after abdominoperineal resection. A penile biopsy was carried out and established the metastatic nature. He underwent palliative chemotherapy treatment. He was still alive 4 months after diagnosis of penile metastases. Conclusion The prognosis of metastasis to the penis is very poor; the best results have been achieved with surgery but only for lesions where metastasis is limited to the penis.

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Section: Discussionmentioning

confidence: 99%

Penile metastases of rectal adenocarcinoma after abdominoperineal resection: a case report

Marghich¹,

Dkhissi²,

Alila³

et al. 2019

J Med Case Reports

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“…Metastasis to the penis are very uncommon, and they are encountered in patients with advanced primary tumors. The vast majority of reported cases has presented with metachronous metastasis and had a history of known primary tumors [ 1 – 3 , 8 , 9 ]. The clinical presentation was usually an ulcerated or a hard mass located on the glans, the penis shaft or the penis root.…”

Section: Discussionmentioning

confidence: 99%

Penile metastasis from rectal adenocarcinoma: a case report

et al. 2017

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BackgroundDespite its rich vasculature, the penis is rarely involved by metastasis. Since the first description of penile metastasis in 1870, fewer than 500 cases have been reported in the literature. The pelvic organs are the main source of primary tumors that metastasize to the penis.Case presentationWe report a case of a 46-year-old Arabic man who presented with erectile dysfunction and painful induration of the penile root. Eight months ago, he had undergone abdomino-perineal resection for rectal adenocarcinoma after neo-adjuvant chemotherapy. The histological evaluation of the resected specimen disclosed a ypT3N0 tumor with a poor therapeutic response (around 5%). An adjuvant chemotherapy by XELOX (oxaliplatin plus capecitabine) regimen has been prescribed for the patient. The magnetic resonance imaging (MRI) showed tumoral infiltration of penile structures and a biopsy of the corpora cavernosa was performed. The histological examination disclosed a penile metastasis from the patient’s previous rectal adenocarcinoma. The patient is still alive and continues his adjuvant therapy.ConclusionPenile secondary tumors are very rare and usually occur in patients with advanced tumor stages. A diagnosis of penile metastasis should be considered in patients with a history of malignancies who present with genitourinary symptoms. These patients have a dismal prognosis as they often die in the year after the diagnosis.

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“…Malignant priapism, penile pain and difficulty in micturition are some of the major presenting symptoms 9. Most cases describing metachronous penile metastasis occur approximately 16–26 months after diagnosis and treatment of the colorectal primary 1 6–10 12–16 19.…”

Section: Discussionmentioning

confidence: 99%

“…However, survival generally does not exceed 2 years unless the metastatic disease is limited to the penis 9 10. In most cases, the average survival of patients with penile metastases treated with chemoradiotherapy is 8 months due to the subsequent development of further metastatic lesions in other organs 14.…”

Section: Discussionmentioning

confidence: 99%

A rare case of metachronous penile and urethral metastases from a rectal mucinous adenocarcinoma

et al. 2015

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SUMMARYMetastatic lesions in the penis are uncommon in patients with prostate or bladder cancer but penile metastatic lesions from rectal tumours are rare with only 65 cases reported in the literature. We describe the case of a 70-year-old man who developed metastatic lesions within his corpus cavernosum 2 years after being diagnosed and treated for a mucinous adenocarcinoma of the rectum and a year after a wedge resection of an isolated lung metastasis. He proceeded with total penectomy and intraoperatively two skip lesions were also found within the wall of his urethra; histological analysis proved that these were also metastatic lesions. A perineal urethrostomy was formed with the remaining macroscopically healthy urethra. He made a good recovery from his operation and continued his treatment under the oncology team. BACKGROUND

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Penile metastases of rectal adenocarcinoma

Abstract: The prognosis of metastasis to the penis is very poor; the best results have been achieved with surgery but only for lesions where metastasis is limited to the penis.

Cited by 14 publications

References 4 publications

Penile metastases of rectal adenocarcinoma after abdominoperineal resection: a case report

Penile metastases of rectal adenocarcinoma after abdominoperineal resection: a case report

Penile metastasis from rectal adenocarcinoma: a case report

A rare case of metachronous penile and urethral metastases from a rectal mucinous adenocarcinoma

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