2017
DOI: 10.1111/andr.12387
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Penile neurovascular structure revisited: immunohistochemical studies with three‐dimensional reconstruction

Abstract: Penile erection is a neurovascular phenomenon that requires well coordinated and functional interaction between penile vascular and nervous systems. In order to provide a useful tool to examine pathologic changes in the erectile tissue, mainly focusing on penile neurovascular dysfunction, we established the technique to determine the differential distribution of endothelial cells, smooth muscle cells, pericytes, and nerve fibers in the mouse penis using immunohistochemical staining with three-dimensional recon… Show more

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Cited by 5 publications
(2 citation statements)
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“…The penis has a specialized vascular bed and penile erection requires well-coordinated interactions between vascular endothelial cells (ECs), smooth muscle cells, pericytes, and neuronal cells [123]. The vascular endothelium plays a critical role in the regulation of blood flow and vascular tone [4].…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…The penis has a specialized vascular bed and penile erection requires well-coordinated interactions between vascular endothelial cells (ECs), smooth muscle cells, pericytes, and neuronal cells [123]. The vascular endothelium plays a critical role in the regulation of blood flow and vascular tone [4].…”
Section: Introductionmentioning
confidence: 99%
“…Pericytes surrounding the ECs of microvessels are known to plays a critical role in maintaining vascular homeostasis [5]. We recently documented the differential distribution of EC and pericytes in the erectile tissue of mice and human by using immunohistochemistry [23].…”
Section: Introductionmentioning
confidence: 99%