Penile prosthesis implantation in the treatment of Peyronie's disease and erectile dysfunction

Carson, C. C.

doi:10.1038/sj.ijir.3900590

Cited by 44 publications

(30 citation statements)

References 14 publications

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“…he standard management of men with combined Peyronie's disease and erectile dysfunction (ED) has been the placement of a penile prosthesis for the correction of both problems [1][2][3][4]. This approach allows restoration of penile anatomy and rigidity and has been associated with high patient satisfaction levels in select patients T [1,4].…”

Section: Introductionmentioning

confidence: 99%

A Surgical Algorithm for Men with Combined Peyronie's Disease and Erectile Dysfunction: Functional and Satisfaction Outcomes

Mulhall

Anderson

Parker

2005

The Journal of Sexual Medicine

114

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Introduction Men with Peyronie's disease who also have erectile dysfunction represent a challenge to the urologist. Historically, penile prosthesis surgery has been the management strategy of choice for this population. This study was undertaken to define the outcomes of a penile reconstructive surgery algorithm in men with Peyronie's disease and concomitant erectile dysfunction (ED). Methods Patients presenting with combined Peyronie's disease and erectile dysfunction were treated with vasoactive therapy initially. All patients underwent dynamic infusion cavernosometry and cavernosography. Nonresponders to erectogenic pharmacotherapy were advised to undergo penile prosthetic surgery. Responders to erectogenic therapy were considered candidates for either corporoplasty or plaque incision and grafting. The International Index of Erectile Function (IIEF) questionnaire was used to compare erectile function and satisfaction profiles serially pre- and postoperatively between the patients in the three groups. Results Sixty-two patients constituted the study population. Eighty-one percent of the patients responded to erectogenic pharmacotherapy. Postoperative IIEF erectile function domain scores were statistically higher for implant patients and lower for plaque incision and grafting patients compared to preoperative scores. Postoperative IIEF satisfaction domain scores were higher for corporoplasty and implant patients and lower for plaque incision and grafting patients compared to preoperative scores. Conclusions The surgical algorithm used in this study leads to excellent IIEF erectile function and satisfaction scores for corporoplasty and implant patients; however, plaque incision and grafting patients had poor functional and satisfaction outcomes. These data support the concept that not all men with combined ED and Peyronie's disease require penile prosthetic surgery, and furthermore, plaque incision and grafting surgery is a poor option for men with combined disease.

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Section: Introductionmentioning

confidence: 99%

A Surgical Algorithm for Men with Combined Peyronie's Disease and Erectile Dysfunction: Functional and Satisfaction Outcomes

Mulhall

Anderson

Parker

2005

The Journal of Sexual Medicine

114

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“…Although malleable prostheses have been used, longterm satisfaction rates are lower than with inflatable devices [131][132][133][134][135][136]. If penile curvature is less than 30°in patients with PD with concomitant erectile dysfunction, placement of inflatable prostheses may be sufficient to achieve penile straightening.…”

Section: Penile Prosthesis Implantationmentioning

confidence: 97%

Treatment of Peyronie’s Disease: 2012 Update

Şerefoğlu

2011

Curr Urol Rep

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Peyronie's disease (PD) is the occurrence of a fibrous inelastic scar of the tunica albuginea of the penis. It is a relatively common disorder among men, with a reported prevalence of 3% to 8%. It is often associated with penile pain, anatomical deformities in the erect state, and difficulty with intromission. Because the exact pathophysiology of PD remains unknown and standards for evaluating or reporting treatment outcomes are unclear, research on effective therapies has been limited. The benefits of nonsurgical treatment options are conflicting and further controlled studies are required before any therapy can be fully recommended. The success of surgery has been well documented; however, surgery is invasive and costly and carries potential side effects. Patients who report stable disease that has been present for longer than 12 months and who experience penile deformity preventing satisfactory sexual intercourse are best suited for surgery. Additionally, failed conservative management and a patient's preference for definitive correction are important additional indications for surgical treatment.

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“…112 The average lifespan of a prosthesis is approximately 10 years, with a 4% mechanical failure at 5 years and 40% failure by 15 years. 113 Success as defined by complete penile straightening ranges from 80 to 93% [114][115][116][117] (Figure 6). …”

Section: Surgical Therapymentioning

confidence: 99%

Peyronie's disease: a critical appraisal of current diagnosis and treatment

2008

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Peyronie's disease is a fibrotic disorder of the tunica albuginea of the penis resulting in varying degrees of penile curvature and sexual dysfunction. Diagnosis of the disorder is made by detailed sexual history and focused physical examination. A wide range of medical treatments has been employed to treat the disorder. Verapamil treatment administered by intraplaque injection is supported by generally consistent randomized controlled trials (RCT). Some RCT evidence exists to support the use of colchicine, potaba, L-carnitine and liposomal superoxide dismutase. Future studies of medical efficacy should focus on improving RCT design, implementation and results reporting to improve the quality of evidence generated by each study. The surgical treatment of Peyronie's disease is a viable and recommended alternative for men with compromised sexual function due to severe curvature or lesions causing penile instability. The choice of corrective procedure should be tailored to each patient after a detailed evaluation of disease severity and sexual function.

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Penile prosthesis implantation in the treatment of Peyronie's disease and erectile dysfunction

Cited by 44 publications

References 14 publications

A Surgical Algorithm for Men with Combined Peyronie's Disease and Erectile Dysfunction: Functional and Satisfaction Outcomes

A Surgical Algorithm for Men with Combined Peyronie's Disease and Erectile Dysfunction: Functional and Satisfaction Outcomes

Treatment of Peyronie’s Disease: 2012 Update

Peyronie's disease: a critical appraisal of current diagnosis and treatment

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