Pentacam sensitivity and specificity in detecting occludable angles

Rossi, Gemma Caterina Maria; Scudeller, Luigia; Delfino, Alessio; Raimondi, Marta; Pezzotta, Sara; Maccarone, Martina; Antoniazzi, Elena; Pasinetti, Giulio Maria; Bianchi, Paolo Emilio

doi:10.5301/ejo.5000108

Cited by 25 publications

(19 citation statements)

References 23 publications

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“…The mean age of the cycloplegia group (Group 1, n=25) was 23.04 ± 3.42 years (range, [18][19][20][21][22][23][24][25][26][27][28][29], while the mean age of the control group (Group 2, n=24) was 22.4 ± 2.05 years (range, [18][19][20][21][22][23][24][25][26][27]. There was no significant difference between the two groups in terms of age or sex distribution (P=0.259 and P=0.878, respectively).…”

Section: Resultsmentioning

confidence: 99%

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Effects of 1% cyclopentolate hydrochloride on anterior segment parameters obtained with Pentacam in young adults

Arıcı¹,

Türk²,

Ceylan³

et al. 2014

Arquivos Brasileiros De Oftalmologia

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Purpose: To investigate the effects of topically applied 1% cyclopentolate hydrochloride on anterior segment parameters obtained with a Pentacam rotating Scheimpflug camera in healthy young adults. Methods: Anterior segment analyses of 25 eyes from 25 young adults (Group 1), before and after 45 min of 1% cyclopentolate hydrochloride application, were performed. For a control group (cycloplegia-free, Group 2), 24 eyes of 24 age-and sex-matched healthy cases were evaluated twice at 45 min intervals. The results obtained from the groups were compared statistically. Results: The mean ages of the groups were 23.04 ± 3.42 (range, 18-29) and 22.4 ± 2.05 (range, 18-27) years for Groups 1 and 2, respectively (p=0.259). In Group 1, measurements between the two analyses were significantly different for the values of anterior chamber depth (ACD), anterior chamber angle (ACA), and anterior chamber volume (ACV) (p<0.05), whereas no statistical difference was found for the central corneal thickness (CCT) and keratometry (K1, K2) measurements. In Group 2, none of these parameters were statistically different between the two analyses. Conclusions: Topically applied 1% cyclopentolate hydrochloride caused an increase in the ACD and ACV values, and a decrease in the ACA value. However, it had no significant effect on the CCT and keratometry measurements. It is important to consider these effects when using the Pentacam device on young adults with cycloplegia and when applying it for various reasons.

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Section: Resultsmentioning

confidence: 99%

“…The ACV and ACA are other important anterior segment parameters in ocular pharmacokinetics and PACG development (26,27) . The cycloplegic effect of 1% cyclopentolate results in the backward movement of the crystalline lens and a decrease in its thickness.…”

Section: Discussionmentioning

confidence: 99%

Effects of 1% cyclopentolate hydrochloride on anterior segment parameters obtained with Pentacam in young adults

Arıcı¹,

Türk²,

Ceylan³

et al. 2014

Arquivos Brasileiros De Oftalmologia

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“…To detect an occludable anterior chamber angle (Van Herick's vs. gonioscopy), sensitivity, specificity and negative predictive values, they were 69, 88 and 94% respectively in a community screening scheme . There is improved accuracy with Pentacam (Oculus, Wetzlar, Germany) and anterior segment OCT but this is not common practice and unlikely to become so because of costs. As technology becomes cheaper, it may acquire a greater role.…”

Section: Preamblementioning

confidence: 99%

Guidelines for the collaborative care of glaucoma patients and suspects by ophthalmologists and optometrists in Australia

White

Goldberg

2014

Clinical Exper Ophthalmology

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“…In effect, although the reported cut-off value of 29.5 degrees has been associated with an area under the receiver operating characteristic curve (AUC) of 0.935, 13 other authors documented similar AUC values to correspond to a cut-off angle of 22.4 degrees. 19 Using a cut-off value of 29.5 degrees, the semiobjective and subjective van Herick estimations and the minimum angle as determined with the Pentacam resulted in a comparable percentage of eyes at risk of angle closure. A cut-off value of 22.4 degrees would have disclosed significant differences between both the semi-objective and subjective van Herick approaches and the Pentacam outcome (all eyes from the current study sample had minimum angles larger than 22.4 degrees).…”

Section: Discussionmentioning

confidence: 93%

“…A conservative cut‐off point was used to investigate the percentage of eyes at risk of ACA closure, as determined by the temporal and the minimum angle values. In effect, although the reported cut‐off value of 29.5 degrees has been associated with an area under the receiver operating characteristic curve (AUC) of 0.935, other authors documented similar AUC values to correspond to a cut‐off angle of 22.4 degrees . Using a cut‐off value of 29.5 degrees, the semi‐objective and subjective van Herick estimations and the minimum angle as determined with the Pentacam resulted in a comparable percentage of eyes at risk of angle closure.…”

Section: Discussionmentioning

confidence: 98%

Sources of variability of the van Herick technique for anterior angle estimation

Gispets

Cardona

Verdú

et al. 2014

Clinical and Experimental Optometry

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Background:The purpose of the present study was to investigate two potential sources of variability of the traditional van Herick technique for temporal anterior chamber angle estimation, namely the need to compare the depth of the peripheral anterior chamber (PACD) with the thickness of the peripheral cornea (PCT), and the possible loss of information resulting from restricting the assessment of the anterior chamber angle (ACA) to the temporal limbus. Methods: Both image analysis and Scheimpflug photography were employed to measure PCT and PACD in a group of 82 eyes (mean ± SD age of 32.8 ± 4.1 years) with and without narrow anterior chamber angles. Subjective and semi-objective van Herick grades were compared and the relationship between PCT and PACD was investigated. Scheimpflug photography was also used to determine the value of the narrowest anterior chamber angle and to compare it with the temporal angle. Results: No statistically significant differences were encountered between semi-objective and subjective grades. A weak statistically significant correlation was found between image analysis values for PCT and PACD (r = 0.295; p = 0.007). Upon examining Scheimpflug photographic data, no statistically significant association between PCT and PACD was revealed. Temporal and minimum anterior chamber angles presented statistically significant differences (t = 7.213; p < 0.001). In approximately 65 per cent of the patients, the minimum ACA was not located at the temporal limbus, with a difference of up to 9.8 degrees between minimum and temporal angles. Conclusion:The encountered association between the image analyses of PCT and PACD advocates for the direct measurement of PACD as a better estimation of ACA depth than the ratio between PCT and PACD. All anterior chamber quadrants should be examined, as the minimum ACA may not be located temporally.

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Pentacam sensitivity and specificity in detecting occludable angles

Abstract: The study pointed out a high power of Pentacam AVA, ACV, and ACD in detecting occludable angles. Pentacam is simple to use, reliable, and noncontact, provides parameters in a short period, and represents a possible screening tool.

Cited by 25 publications

References 23 publications

Effects of 1% cyclopentolate hydrochloride on anterior segment parameters obtained with Pentacam in young adults

Effects of 1% cyclopentolate hydrochloride on anterior segment parameters obtained with Pentacam in young adults

Guidelines for the collaborative care of glaucoma patients and suspects by ophthalmologists and optometrists in Australia

Sources of variability of the van Herick technique for anterior angle estimation

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