Pentaerythritol Jetranitrate in the Jreatment of Angina Pectoris

Kalmanson, George M.

doi:10.1001/archinte.1955.00250120055006

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1958

1975

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Cited by 14 publications

(2 citation statements)

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“…Russek (1966), in a double-blind study, found pentaerythritol tetranitrate produced a significant increase in exercise tolerance when administered before meals. On the other hand, Kalmanson et al (1955) in their double-blind study failed to demonstrate any beneficial effect of this drug on angina pectoris.…”

Section: Discussionmentioning

confidence: 96%

Anti-anginal drugs

Goldbarg¹,

Paxinos²,

Miller³

1970

Postgraduate Medical Journal

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Section: Discussionmentioning

confidence: 96%

Anti-anginal drugs

Goldbarg¹,

Paxinos²,

Miller³

1970

Postgraduate Medical Journal

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“…This level of response is the probable explanation for the continued prescribing of long‐acting nitrates in the treatment of angina. Critical examination of their value (Kalmanson et al , 1955; Today's Drugs, 1967) reveals no evidence of longterm therapeutic benefit.…”

Section: Discussionmentioning

confidence: 99%

A Total of 254 cases of Angina Pectoris treated with Oxprenolol in Hospital Practice — a Monitored Release Study

Forrest¹

1972

Int J Clinical Practice

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Physicians were asked to diagnose "Angina of effort, of sufficient severity to interfere with the qualities of the patient's life". There is little doubt, on reviewing the record forms, that all cases represented true ischaemic angina and were not confused with cases of Da Costa's syndrome. Dosage and Response Tillie:The nunuuum recommended dosage of oxprenolol was 120mg. daily (40mg. t.i.d.j, Physicians were asked to assess the optimum dosage until the maximum response was achieved. The dosage ranged from 120 to 480mg. daily with a mean dosage of 180mg. daily, and the distribution is illustrated in }<'ig, I.angina for more than 5 years and II % for more than 10 years; 33% of the patients gave a history of previous myocardial infarction. 56% of the group were being treated with trinitrin only, 32% with trinitrin and a longacting nitrate; 10% were being treated with a betahlocking drug, other than oxprenolol (usually with trinitrin additionally). 25% of the group had previously been treated with a heta-hlocking drug.In summary, this represents a typical cross-section of angina patients, well suited to provide clinical information on efficacy and tolerability of treatment.

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Progress in the Long-Term Management of Coronary Artery Disease

Sambhi¹

1958

Arch Intern Med

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Pentaerythritol Jetranitrate in the Jreatment of Angina Pectoris

Cited by 14 publications

References 7 publications

Anti-anginal drugs

Anti-anginal drugs

A Total of 254 cases of Angina Pectoris treated with Oxprenolol in Hospital Practice — a Monitored Release Study

Progress in the Long-Term Management of Coronary Artery Disease

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