Pentaerythritol Tetrasalicylate in the Chemical Composition of Root Canal Sealers

Silva, Manuela Gonçalves de Souza e; Münchow, Eliseu Aldrighi; Vitti, Rafael Pino; Sinhoreti, Mário Alexandre Coelho; Piva, Evandro; Ogliari, Fabrício Aulo; Zanchi, César Henrique

doi:10.1590/0103-6440201801441

Cited by 2 publications

(1 citation statement)

References 21 publications

(42 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In 1995, one of the representatives of epoxy resin-based sealers, AH Plus (Dentsply De Trey GmbH, Konstanz, Germany), was introduced as a two-component system and had properties such as adequate seal, wettability, and antimicrobial activity [ 10 ]. The usage of salicylate resin as one of the components in the endodontic sealer matrix is proven to influence the physicochemical and cytotoxicity properties of the sealer [ 11 ]. With the introduction of calcium hydroxide-based sealers with salicylate components such as Sealapex (SybronEndo, Orange, CA, USA), a significant increase in antibacterial properties was witnessed, mainly due to alkaline pH properties causing denaturation of bacterial proteins, making them less toxic to vital tissues.…”

Section: Introductionmentioning

confidence: 99%

Influence of Commonly Used Endodontic Irrigants on the Setting Time and Metal Composition of Various Base Endodontic Sealers

et al. 2021

View full text Add to dashboard Cite

The present study aimed to evaluate if commonly used endodontic irrigants such as 3% sodium hypochlorite (NaOCl, Prime Dental, Thane, India), 2% chlorhexidine (CHX, Sigma-Aldrich Co., St. Louis, MO, USA), and 17% ethylenediaminetetraacetic acid (EDTA, Meta-Biomed Co. Ltd., Cheongju-si, South Korea) influenced the setting time and metal composition of different base endodontic sealers on exposure. AH Plus (Dentsply De Trey GmbH, Konstanz, Germany), Sealapex (SybronEndo, Orange, CA, USA), mineral trioxide aggregate (MTA) Fillapex (Angelus Soluções Odontológicas, Londrina, Brazil), and Tubli-Seal (Kerr Dental, Orange, CA, USA) were selected as the different base representatives of endodontic sealers. These sealers were exposed to 3% NaOCl, 2% CHX, and 17% EDTA, and the individual setting time of the sealers was analyzed. The samples were analyzed for heavy metal elements such as chromium (Cr), nickel (Ni), cobalt (Co), cadmium (Cd), arsenic (As), mercury (Hg), lead (Pb), and beryllium (Be) by using inductively coupled plasma mass spectrometry (ICP-MS) analysis. For statistical analysis, one-way ANOVA and post hoc Tukey’s tests were used. All selected sealers showed variation in setting time post-exposure to different irrigants. MTA Fillapex had the shortest mean setting time (215.7 min, post-exposure at 187.3 min) (p < 0.05). Mean setting time was also affected for AH Plus (479.6 min, post-exposure at 423.9 min) (p < 0.05) and Tubli-Seal (514.7 min, post-exposure at 465.2 min) (p < 0.05). Sealapex showed the maximum reduction of setting time (864.8 min, post-exposure at 673.4 min) (p < 0.05). All tested sealers showed heavy metals (Cr, Ni, Co, Cd, As, Hg, and Pb) in their composition, and the quantities were influenced by interaction with different irrigants. The heavy metal Be was not seen in any of the samples. Sealapex showed the longest setting time in comparison to other test sealers. Heavy metals were most present in Sealapex, followed by AH Plus, Tubli-Seal, and MTA Fillapex. MTA Fillapex was seen to have the shortest setting time, and heavy metal composition was least affected on interaction with different commonly used endodontic irrigants. Further, this study provides significant insight into the influence of different endodontic irrigants on interaction with different base endodontic sealers, which has not been reported previously, and future studies should emphasize endodontic irrigant-sealer interactions and their possible effects in the long run.

show abstract

Section: Introductionmentioning

confidence: 99%

Influence of Commonly Used Endodontic Irrigants on the Setting Time and Metal Composition of Various Base Endodontic Sealers

et al. 2021

View full text Add to dashboard Cite

show abstract

Synthesis, physical properties, and root canal sealing of experimental MTA- and salicylate-based root canal sealers

Vitti,

Cardoso,

Pereira

et al. 2024

Preprint

View full text Add to dashboard Cite

Objectives: To develop and evaluate the physical properties and sealing ability within the root canal of three experimental sealers based on MTA and a salicylate resin. Materials and Methods: The experimental sealers were composed of two pastes. The base paste was prepared using 1,3-butyleneglycol disalicylate and bismuth oxide. Three different catalytic pastes were formulated, creating three groups: [MTA] n,n,dihydroxyethyl-p-toluidine (DPT), titanium dioxide (TiO2), and mineral trioxide aggregate (MTA); [MTA-HA] DPT + TiO2 + MTA + hydroxyapatite (HA); and [MTA-DCPD] DPT + TiO2 + MTA + dibasic calcium phosphate dihydrate (DCPD). MTA Fillapex (Angelus) was used as the commercial reference (control). The sealers were manipulated at a 1:1 ratio (base paste:catalyst). Tests for working time and setting time, flow, and film thickness were conducted following ISO 6876:2012 standards. Single-rooted human teeth root canals were utilized for evaluating root canal filling using micro-computed tomography, push-out bond strength testing, and sealer penetration into dentinal tubules using confocal microscopy. Failure patterns in the push-out test were classified as adhesive, cohesive, or mixed. Sealer micromorphology was analyzed via scanning electron microscopy. Data were analyzed statistically (α=0.05). Results: MTA Fillapex showed the longest working and setting times, highest flow, the lowest film thickness, and better penetration into dentinal tubules. There was no difference in void among evaluated sealers. Overall, MTA-DCPD sealer showed the lowest bond strength values for cervical and apical thirds. Micromorphological analysis revealed similar crystallographic properties among all sealers. Conclusions: The sealers tested showed reduced working and setting times, with flow and film thickness according to ISO 6876:2012. Their void volume and bond strength were similar to MTA Fillapex, except for MTA-DCPD. Clinical Relevance: The experimental root canal sealers demonstrated suitable physical properties and good adaptation within the root canal.

show abstract

Pentaerythritol Tetrasalicylate in the Chemical Composition of Root Canal Sealers

Cited by 2 publications

References 21 publications

Influence of Commonly Used Endodontic Irrigants on the Setting Time and Metal Composition of Various Base Endodontic Sealers

Influence of Commonly Used Endodontic Irrigants on the Setting Time and Metal Composition of Various Base Endodontic Sealers

Synthesis, physical properties, and root canal sealing of experimental MTA- and salicylate-based root canal sealers

Contact Info

Product

Resources

About