Pentoxifylline and/or praziquantel reduce murine schistosomiasis mansoni histopathology via amelioration of liver functions

Molluscicidal activity of sodium hypochlorite against Biomphlaria alexandrina snails: Immunological and hepato-endocrine alterations with in silico docking study

“…Praziquantel is a widely used anthelmintic against parasites that proved efficiency against trematodes and cestodes and is the only approved drug against schistosomiasis ( Ibrahim et al, 2019 ; Ibrahim et al, 2022b ). Praziquantel has efficacy against adult worms, but poorly active against juvenile stages and for that reason, it must be periodically applied for effective treatment and control ( Ibrahim et al, 2019 ).…”

“…Praziquantel is a widely used anthelmintic against parasites that proved efficiency against trematodes and cestodes and is the only approved drug against schistosomiasis ( Ibrahim et al, 2019 ; Ibrahim et al, 2022b ). Praziquantel has efficacy against adult worms, but poorly active against juvenile stages and for that reason, it must be periodically applied for effective treatment and control ( Ibrahim et al, 2019 ). The heavy use of Praziquantel for treatment of schistosomiasis, resulted in high-resistance as reported in the study conducted by ( Ismail et al, 1994 ) who reported that despite the use of praziquantel in some cases, the infection persisted.…”