The purpose of the article is to highlight the peculiarities of fundamental and applied forms of social inequality in the context of cultural and historical experience and prospects of civilisational development. Social differentiation has a diverse character, which forms the diversity of parameters of this socio-cultural phenomenon. The purpose of scientific research is to unify social indicators that activate and determine the level of inequality in society. Social processes are marked by contradictions in the worldview and mental understanding, so the issue of inequality is regulated by clear and understandable theoretical, methodological, legal, and socio-cultural guidelines. The research methodology is focused on the scientific and sociological methodological cluster. A sociological study based on content analysis, monitoring, and expert opinions allows us to determine the structure and manifestations of social inequality. Long-term sociological observations and in-depth analytical descriptions form the constants of the fundamental nature of social inequality. The results of the study emphasise the need to correlate the fundamental understanding of social inequality and the applied manifestation of this phenomenon in the socio-cultural space. In today's dynamic world, traditional and sustainable interpretations of inequality are hardly accepted, since the current principles of social development involve rapid permanent changes that determine the parameters of social inequality almost online. Under such conditions, society needs new flexible parameters that will determine the quantitative and qualitative parameters of social inequality. Thus, social inequality is an integral element of cultural and historical experience, having formed the fundamental dimensions of this phenomenon, while its prospects require regulation by society to avoid and mitigate the negative impact of social inequality in the form of injustice, discrimination, chauvinism, etc. Promising areas of research on the problem of social inequality include focusing on the dynamics of the social structure, which fundamentally changes the fundamental and targeted understanding of social inequality, leading to inadequate assessments of threats associated with the direct manifestation of social inequality in society.