People without clinical diagnosis of intolerance or allergy have benefits from gluten-and casein-free diet

Abstract

Introduction and Aim: The present study aimed to assess university professors and students regarding the variation in body mass and intestinal health resulting from a restricted dietary intervention in foods containing gluten and casein. Methods: This was a non-randomized, quasi-experimental clinical trial type study. Initially, 122 volunteers aged 20 to 55 years of both sexes were evaluated, but only 63 volunteers comprised the final sample. Participants were divided into two groups: No Gluten/Casein containing Food Restriction (CG, n= 42) and Gluten/Casein containing Food Restriction (EG, for 90 days, n= 21). Approval was obtained from the Ethics Committee on Human Research at the Health Sciences Center of the Federal University of Pernambuco under protocol number 5.671.846. It also presents the Brazilian Clinical Trials Registry (ReBEC) under number RBR-6htr5rg. Results: Scores from the Metabolic Screening Questionnaire (MSQ) in the intervention group for the thick domain showed a significant improvement compared to the NGC. Additionally, within-group comparisons showed reduced scores in the overall MSQ and domains of the digestive tract, mind, head, and emotions (p=<0.0001; p=0.0003; p=0.0434; p=0.0143; p=0.0318; respectively). Improvement in responses to the Bristol Scale was observed after gluten-and casein-free diet (GCFD). There was no reduction in body mass or Body Mass Index (BMI). Conclusion: These results confirm our hypothesis that GCFD seems to contribute to improve intestinal function in people without diagnosed intolerances/allergies to these components. Making it a pioneer in the outlined research design.