Pepper and Capsaicin (<i>Capsicum</i>and<i>Piper</i>Species)

Barceloux, Donald G.; Faact,; Facmt,

doi:10.1002/9780470330319.ch10

Medical Toxicology of Natural Substances 2008

DOI: 10.1002/9780470330319.ch10

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Pepper and Capsaicin (CapsicumandPiperSpecies)

Donald G. Barceloux

Faact Faact²,

Facmt Facmt³

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Cited by 3 publications

References 44 publications

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Capsaicin, a potential inhibitor of cholera toxin production inVibrio cholerae

Chatterjee

Asakura

Chowdhury

et al. 2010

FEMS Microbiology Letters

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The use of natural compounds as inhibitory agents for virulence factor production is a new approach to overcome increased antimicrobial resistance in pathogenic bacteria. In this study, we examined whether red chilli (Capsicum annuum) contains any such compound(s) that can repress the cholera toxin (CT) production in Vibrio cholerae. We found that the methanol extract of red chilli could inhibit CT production in recently emerged V. cholerae O1 El Tor variant strains without affecting their viability. Interestingly, capsaicin, a well-studied active component of red chilli, also drastically inhibited CT production in V. cholerae strains belonging to various serogroups including variants. Real-time quantitative reverse transcription-PCR assay revealed that capsaicin effectively repressed the transcription of ctxA, tcpA and toxT genes, but not of toxR and toxS genes. On the contrary, capsaicin significantly enhanced the transcription of the hns gene, the product of which is known to regulate negatively the transcription of ctxAB, tcpA and toxT genes. These results suggest that capsaicin might act as a potent repressor for CT production possibly by enhancing the transcription of hns.

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Capsaicin, a potential inhibitor of cholera toxin production inVibrio cholerae

Chatterjee

Asakura

Chowdhury

et al. 2010

FEMS Microbiology Letters

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Lectotypifications, synonymy, and a new name in Capsicum (Solanoideae, Solanaceae)

Barboza¹

2011

PHYTOKEYS

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Considerable confusion exists within Capsicum (Solanaceae) regarding the status and typification of several names, in part due to misidentifications. Some types were destroyed in Berlin during the Second World War, some have not been found by modern systematics, while others exhibit uncertain locality data or contain material from more than one species. Fourteen lectotypes, synonyms, and a new name, Capsicum eshbaughii Barboza nom. nov.,are proposed here.

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Biochemical Investigation of Leaf Development in Capsicum frutescens

Ahmed¹

2013

JAS

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The objective of this research was to investigate the developmental regulation of cell wall components and development of leaves of Capsicum frutescens. In order to this, a growth curve was constructed of lengths and widths of fifty Capsicum frutescensleaves measured until growth had stopped (20 days). From the curve, four developmental stages were selected and harvested for further study. A range of proteins with molecular weights from 13.4 to 44 kDa were detected in selected samples by SDS-PAGE. A total of four protein bands C, D, K and L with molecular weights 36.2, 27.7, 16.8 and 16.0 kDa respectively were developmentally regulated during the leaf development. This data provide the basis for further more detailed molecular analyses of leaf development in this research.

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Pepper and Capsaicin (CapsicumandPiperSpecies)

Cited by 3 publications

References 44 publications

Capsaicin, a potential inhibitor of cholera toxin production inVibrio cholerae

Capsaicin, a potential inhibitor of cholera toxin production inVibrio cholerae

Lectotypifications, synonymy, and a new name in Capsicum (Solanoideae, Solanaceae)

Biochemical Investigation of Leaf Development in Capsicum frutescens

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