Peptic Ulcer

Jh, Baron

doi:10.1016/s0140-6736(75)93174-8

Cited by 39 publications

(3 citation statements)

References 3 publications

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“…It dates back to 1670, when king Charles I's daughter, Henriette-Anne died suddenly after a day of abdominal pain and tenderness. Poisoning was suspected and an autopsy was performed, during which a small hole was found in the anterior abdominal wall, with signs of peritonitis [1,2]. Autopsies came into effect from 1500 AD [2,3], since when many patients with pain in the abdomen and vomiting, who died, were found to have holes in the anterior wall of the stomach during their autopsies.…”

Section: Introductionmentioning

confidence: 99%

“…Poisoning was suspected and an autopsy was performed, during which a small hole was found in the anterior abdominal wall, with signs of peritonitis [1,2]. Autopsies came into effect from 1500 AD [2,3], since when many patients with pain in the abdomen and vomiting, who died, were found to have holes in the anterior wall of the stomach during their autopsies. PPUs occur in 2-10% of the patients with peptic ulcer disease and they account for more than 70% of the deaths which are associated with Peptic Ulcer Disease (PUD).…”

Section: Introductionmentioning

confidence: 99%

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The Perforation-Operation time Interval; an Important Mortality Indicator in Peptic Ulcer Perforation

Surapaneni¹,

Vb²

2013

JCDR

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Objective: To find out the significance of the PerforationOperation Interval (POI) with respect to an early prognosis, in patients with peritonitis which is caused by peptic ulcer perforation.Study Design: Case series. Materials and Method:This study included 150 patients with generalized peritonitis, who were diagnosed to have Perforated Peptic Ulcers (PPUs). The diagnosis of the PPUs was established on the basis of the history , the clinical examination and the radiological findings. The perforation-operation interval was calculated from the time of onset of the symptoms like severe abdominal pain or vomiting till the time the patient was operated.Result: Out of the 150 patients 134 were males and 16 were females, with a male : female ratio of 9:1. Their ages ranged between 25-70 years. Out of the 150 patients, 65 patients (43.3%) presented within 24 hours of the onset of severe abdominal pain (Group A), 27 patients (18%) presented between 24-48 hours of the onset of severe abdominal pain (Group B) and 58 patients (38.6%) presented after 48 hours. There was no mortality in Group A and the morbidity was more in Group B and Group C. There were 15 deaths in Group C. Conclusion:The problem of peptic ulcer perforation with its complication, can be decreased by decreasing the perforation -operation time interval, which as per our study, appeared to be the single most important mortality and morbidity indicator in peptic ulcer perforation.SuShama Surapaneni, rajKumar S, Vijaya bhaSKar reddy a.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The Perforation-Operation time Interval; an Important Mortality Indicator in Peptic Ulcer Perforation

Surapaneni¹,

Vb²

2013

JCDR

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“…King Charles first daughter, Henriette-Anne, died in 1670 after a day of abdominal pain and tenderness. Since poisoning was suspected autopsy was performed revealing peritonitis and a small hole in the anterior wall of stomach 1,2 . Every year peptic ulcer disease affects 4 million people around the world and 2%-14% of these ulcers perforate 3,4 .…”

Section: Introductionmentioning

confidence: 99%

A Clinical Study of Peptic Ulcer Perforation

Vaswani

Bhamre

2018

MVP Journal of Medical Sciences

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Background: Perforation is one of the most important complications of a peptic ulcer. In spite of modern management, it is still a life threatening emergency. Operative method is still the treatment of choice and simple closure of perforation with Graham's patch is an established procedure of choice in our institution. Material and Methods: A prospective study was conducted on 30 diagnosed patients of perforated peptic ulcer at Dr. Vasantrao Pawar Medical College, Nashik to study the clinical profile and clinical outcome of peptic ulcer perforation patients post operatively from August 2014 to December 2016. Results: A total of 30 patients were included, majority of patients presented in the 4 th decade of life and 88.67% were males, 76.67% of the total patients had positive history suggestive of peptic ulcer disease and 36.66% patients had associated co morbidities, (36.67%) had severe dehydration, 10% patients presented with hypotension, with a systolic blood pressure of less than 90mmHg. In 23.33% of patients surgery was performed within 5 days of onset of acute abdominal pain and 16.67% presented with severe contamination of the peritoneal cavity, 33.33% presented with gastric perforation and 66.67% presented with duodenal perforation. 30% patients suffered from post operative wound infection and 30% patients suffered from post-operative respiratory infections. 16.67% patients presented with post operative sepsis. The mortality rate in this study was 10%. Conclusion: Perforated peptic ulcer is one of the most commonest acute abdominal emergencies. The outcome of the patient depends on the age of the patient, associated co morbidities, time interval between acute abdominal pain and surgery, timely resuscitation, contamination of the abdomen and post operative sepsis.

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