Peptic Ulcer Disease

Holton, John

doi:10.1016/b978-0-12-374934-5.00049-0

Essentials of Genomic and Personalized Medicine 2010

DOI: 10.1016/b978-0-12-374934-5.00049-0

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Peptic Ulcer Disease

John Holton¹

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2019

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Floating Drug Delivery Systems: An Emerging Trend for the Treatment of Peptic Ulcer

Namdev

Jain

2019

CDD

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: Floating drug delivery system (FDDS) is the main approach to prolonging the gastric residence time in the stomach in which the bilayer floating tablet has the main role. It is more suitable for the treatment of local infections such as peptic ulcer, gastritis, Zollinger-Ellision syndrome, indigestion, and other local infections related to the gastrointestinal tract and also used for systemic applications. FDDS provides protection for those drugs which are acid labile and have a short half-life. It also improves bioavailability, reduces drug waste, and enhances the residence time of drugs. Nowadays, various technologies are being used for the development of FDDS. Novel drug delivery systems incorporation into bilayer floating tablets have also broadened the role of FDDS. Polymers have the main role in the development of FDDS, which serve as carriers for the drug and determine the gastric retention time and drug protection. FDDS is also an easy, cheap, and more convenient method for dual drug delivery of drugs.

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Floating Drug Delivery Systems: An Emerging Trend for the Treatment of Peptic Ulcer

Namdev

Jain

2019

CDD

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Peptic Ulcer Disease

Cited by 1 publication

References 250 publications

Floating Drug Delivery Systems: An Emerging Trend for the Treatment of Peptic Ulcer

Floating Drug Delivery Systems: An Emerging Trend for the Treatment of Peptic Ulcer

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