“…[27][28][29][30][31][32] In recent decades, the variety of peptide sequences employed in PAs has been greatly expanded, [33] as well as their applications ranging from neural tissue regeneration [34] to drug delivery, [35,36] antimicrobial systems, [37] peptide vaccines, [38,39] immune-therapeutic applications [40,41] and non-viral gene delivery. [42][43][44] For instance, by attaching a fatty acid residue to antibacterial [37,45] and antiviral peptides, [46][47][48][49][50][51] their potency was greatly improved. Recent works have shown that PAs are internalized via lipidraft mediated endocytosis by a variety of cell lines without affecting cell viability.…”