Peptide-induced patterning of gold nanoparticle thin films

Nanoadsorbents: Classification, Preparation, and Applications (with Emphasis on Aqueous Media)

“…Although gold nanoparticles are among the most intensely studied nanoscale materials, the actual mechanisms of their formation often remain unclear due to limited accessibility to in-situ -derived time-resolved information about precursor conversion and particle size distribution . Although various strategies for modification of the gold NP surface have been established, including additional coating, ligand modification, and ligand exchange, after 10 years of extensive studies the synthesis of functionalized gold NPs still presents a major challenge, especially in cases when the desire is to conjugate a defined number of types of biomolecules onto the surface of individual gold NPs. , Plenty of methods have been published in the past decades, including the classical citrate synthesis procedure via in situ SAXS and XANES using synchrotron radiation (Figure ), two-step UV irradiation–reduction, thermal UV irradiation reduction by citrate and ascorbic acid, deposition–precipitation (DP), direct anionic exchange (DAE), photocatalytic deposition (PD), sonication–reduction of HAuCl 4 , , peptide-induced deposition (Figure ), surfactant-free, surface-bound interdigitated bilayers, pulsed laser-induced ablation from solid targets, , and sol–gel. − …”

Rational Design of Functional Peptide–Gold Hybrid Nanomaterials for Molecular Interactions

“…[ 293 ] Particular interests have been directed toward employing peptides to facilitate the assembly/synthesis process due to their chemical flexibility and versatility. [ 294–300 ] Despite the general targeting function of peptide–gold played in gene therapy, [ 20,204,301,302 ] peptide–AuNP conjugates have also been utilized for kinetic studies which revealed details on the effect of protease activity [ 303 ] and aggregation progress [ 304 ] that helps the improvement of existing assays. Most interestingly, peptide–AuNP ensembles have been demonstrated to greatly enhance the transesterification of the p ‐nitrophenyl ester of N‐carboxybenzylphenylalanine (by over two orders of magnitude).…”

Biomolecule-functionalized polymer brushes

“…The ability to pattern biomolecules onto a substrate is of crucial importance to a variety of biological applications, including biochips, biosensors, microarrays and cell growth regulation/ patterning, and applications based on cell-surface interactions. [92][93][94][95][96] PAA grafted-PC film surfaces were patterned to bind biomolecules. 69 Patterning surfaces can be achieved via a variety of methods, including UV irradiation through a photomask 71,73 and electron-beam.…”