Peptides from Animal Venom and Poisons

Oliveira, Ana; Soares, Andreimar M.; Silva, Saulo L. da

doi:10.1007/s10989-023-10557-8

Cited by 1 publication

(1 citation statement)

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“…Peptides found in venom can interact with certain biological components. This offers potential for the development of new medications that can target prevalent diseases like cancer and neurological disorders ( 60 ). The intricated and expensive endeavor of manufacturing novel medications from toxins necessitates substantial financial commitment, especially throughout the clinical stages of II and III, with no assurance of success ( 60 ).…”

Section: Peptides With Anticancer Functionmentioning

confidence: 99%

Bioactive peptides: an alternative therapeutic approach for cancer management

Ghadiri,

Javidan,

Sheikhi

et al. 2024

Front. Immunol.

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Cancer is still considered a lethal disease worldwide and the patients’ quality of life is affected by major side effects of the treatments including post-surgery complications, chemo-, and radiation therapy. Recently, new therapeutic approaches were considered globally for increasing conventional cancer therapy efficacy and decreasing the adverse effects. Bioactive peptides obtained from plant and animal sources have drawn increased attention because of their potential as complementary therapy. This review presents a contemporary examination of bioactive peptides derived from natural origins with demonstrated anticancer, ant invasion, and immunomodulation properties. For example, peptides derived from common beans, chickpeas, wheat germ, and mung beans exhibited antiproliferative and toxic effects on cancer cells, favoring cell cycle arrest and apoptosis. On the other hand, peptides from marine sources showed the potential for inhibiting tumor growth and metastasis. In this review we will discuss these data highlighting the potential befits of these approaches and the need of further investigations to fully characterize their potential in clinics.

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Section: Peptides With Anticancer Functionmentioning

confidence: 99%