Peptides influence retinal ganglion cells

Dick, Evan; Miller, Robert F.

doi:10.1016/0304-3940(81)90338-4

Cited by 87 publications

(31 citation statements)

References 7 publications

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“…It has been demonstrated, however, that SP iontophoresed onto ganglion cells of the mudpuppy retina is excitatory (Dick and Miller, 1981). This result is consistent with more recent findings in other vertebrates.…”

Section: Substance P-like Immunoreactivesupporting

confidence: 90%

Distribution and regulation of substance P‐related peptide in the frog visual system

Debski

2001

Microscopy Res & Technique

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Modulation of visual signal activity has consequences for both signal processing and for activity-dependent structuring mechanisms. Among the neuromodulatory agents found in visual areas are substance P (SP)-related peptides. This article reviews what is known about these substances in the amphibian retina and optic tectum with special emphasis on the leopard frog, Rana pipiens. It is found that the distribution of these SP-related peptides is remarkably similar to that seen in mammals. This suggests that study of model amphibian systems may significantly enhance our understanding of how neuropeptides contribute to visual system function and organization.

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Section: Substance P-like Immunoreactivesupporting

confidence: 90%

Distribution and regulation of substance P‐related peptide in the frog visual system

Debski

2001

Microscopy Res & Technique

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“…The role of such peptides is uncertain but each appears to be largely confined to a distinctive cell population (Stell et al, 1980). Neuropeptides have been found capable of altering the excitability of retinal ganglion cells (Djamgoz et al, 1981, Dick andMiller, 1981).…”

Section: Discussionmentioning

confidence: 99%

Neurotransmitter-related features of the retinal pigment epithelium

Bondy

Ali

Hong

et al. 1983

Neurochemistry International

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“…The function of SP in retinal processing is unknown. In physiological experiments, application of SP causes a general increase in ganglion cell activity without affecting its receptive field [Dick and Miller, 1981;Glickman et al, 1982]. The effect of SP is relatively long-lasting, compared to its presence in the perfusion bath.…”

Section: Discussionmentioning

confidence: 99%

Interspecific Comparisons of Immunohistochemical Localization of Retinal Neurotransmitters in Four Species of Bats

Studholme

Yazulla²,

Phillips³

1987

Brain Behav Evol

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Four ecologically distinctive Neotropical bat species of the family Phyllostomidae were collected and their retinae surveyed immunohistochemically for the presence of neurotransmitter candidates: glucagon, somatostatin, vasoactive intestinal peptide, substance P (SP), methionine enkephalin, serotonin (5-HT) and two enzymes, glutamic acid decarboxylase (GAD) and tyrosine hydroxylase (TOH). In all four species immunoreactivity (IR) to GAD, TOH and SP was found. GAD-IR and SP-IR showed little interspecies variation whereas TOH-IR differed interspecifically in a pattern that matched the systematic relationships and the ecological characteristics of the bats. 5-HT-IR, which has not previously been reported from mammalian retinae, was found in fibers in the inner nuclear layer and in the outer and inner plexiform layers of Macrotus waterhousii, which is a relatively underived insectivorous phyllostomid bat, but was not found in the retinae from frugivorous or nectarivorous species.

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Peptides influence retinal ganglion cells

Cited by 87 publications

References 7 publications

Distribution and regulation of substance P‐related peptide in the frog visual system

Distribution and regulation of substance P‐related peptide in the frog visual system

Neurotransmitter-related features of the retinal pigment epithelium

Interspecific Comparisons of Immunohistochemical Localization of Retinal Neurotransmitters in Four Species of Bats

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