Introduction: Cinnamomum burmannii (Nees & T. Nees) Blume which has the main content of Cinnamaldehyde has an anti-inflammatory effect. Research on the antiinflammatory effect of the essential oil of the bark of C. burmannii from Kerinci Regency (CBOK) has been conducted. Methods: The anti-inflammatory test of CBOK was carried out using Wistar rats. The anti-inflammatory test was carried out by using the paw test. The volume increase in paw due to swelling were measured. Histopathological analysis was performed by counting inflammatory cells and expression of TNF-α. The data analyzed were edema volume inhibition, the number of inflammatory cells and the expression of TNF-α. Results: There was a significant difference in the increase in inhibition of edema in the administration of CBOK compared to the negative control. A decrease in the number of inflammatory cells and TNF-α expression were observed. Thus, in this study of CBOK has anti-inflammatory effects.