Peran Lemak Epikardial Pada Penyakit Jantung Koroner Stabil

Abstract

<p><em>Visceral fat tissue widely known have endocrine function by secreting Cytokines that provide it function in metabolism of visceral organ such as heart. It function have pivotal role under physiology and patology condition by secreting antiinflamatory cytokines in physiology condition, otherwise proinflammatory cytokines in patology condition. Epicardial fat tissue as regard this function, have more important role to the heart, because it have two advantage than other visceral depots. First, this tissue have same microcirculation provided by small branch of coronary arteries, and second it were not boundary by any structure. Recent studies found that there were correlation between increased epicardial fat depot and coronary artery disease. It seems correlate with this unique structure and function. This literature review focuse on how is the role of epicardial fat tissue in atheroschlerotic process especially in coronary artery.</em></p>

Evaluation of Visceral Fat Volume Extracted from Abdomen CT-Scan Images using Computer Aided Diagnosis (CAD)

“…From Table 3, information is obtained that the area of visceral fat in women is greater than the area of visceral fat in men, which is 83.71 cm 2 with a total volume of visceral fat of 1739.8 cm 3 . Whereas in men, the visceral fat area is 70.82 cm 2 with a total volume of 1036.23 cm 3 . In 2002, a Japanese study on 1,193 patients found that the VFA (Visceral Fat Area) value of 100 cm 2 is a proper cut-off for predicting patients with more than one clinical diagnosis, such as dyslipidemia, hyperglycemia, and hypertension.…”

“…Subcutaneous fat will be distributed as much as 80-90% into the body. At the same time, visceral fat is stored in the abdominal cavity, associated with the digestive tract, as much as 10-20% [3]. Visceral fat tissue is one of the tissues that can secrete cytokines that play a role in the function and metabolism of the visceral organs, including the heart [4].…”

“…One of the diagnostic tools is a Computerized Tomography Scan (CT-scan), the image produced by a CT-scan with a contrast agent can show differences between body structures more clearly than a non-contrast CT-scan image [5][6][7][8]. Therefore, CT-scan images with contrast are often used for fat volume quantification [3]. So in practice, CT scanning has become the gold standard in determining the amount of visceral adipose tissue, which is a direct index of visceral adiposity [9].…”