“…9,10 Ca(Si2O5) is often used as an endodontic material, especially in treating pulpal regeneration and hard tissue repairs such as pulp capping, apexogenesis, pulpotomy, apexification, root-end filling and perforation repair. 11,12,13 Ca(Si2O5), when in contact with oral fluids, can release calcium, silicate hydrate and calcium hydroxide. 14 Calcium hydroxide releases calcium ions that play a role in cell adhesion, migration, differentiation and proliferation.…”