Type-D personality predicts chronic anxiety following percutaneous coronary intervention in the drug-eluting stent era Spindler, H.; Pedersen, S.S.; Serruys, P.W.; Erdman, R.A.M.; van Domburg, R.T.
Published in: Journal of Affective Disorders
Document version:Publisher's PDF, also known as Version of record
Publication date: 2007
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Citation for published version (APA):Spindler, H., Pedersen, S. S., Serruys, P. W., Erdman, R. A. M., & van Domburg, R. T. (2007). Type-D personality predicts chronic anxiety following percutaneous coronary intervention in the drug-eluting stent era. Journal of Affective Disorders, 99(1-3), 173-179.
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Take down policyIf you believe that this document breaches copyright, please contact us providing details, and we will remove access to the work immediately and investigate your claim. Abstract Background: Anxiety is an often overlooked risk factor in coronary artery disease (CAD). Hence, little is known about predictors of unremitting chronic anxiety in CAD patients. We examined whether the distressed personality (type-D) predicts chronic anxiety post percutaneous coronary intervention (PCI). Methods: Unselected patients (n = 167) treated with PCI using sirolimus-eluting or bare metal stents as part of the RESEARCH registry, who were anxious 6 months post-PCI, qualified for inclusion. Patients completed the Hospital Anxiety and Depression Scale at 6 and 12 months and the Type-D Scale (DS14) 6 months post-PCI. Results: Of 167 patients anxious at 6 months, 108 (65%) were still anxious 12 months post-PCI. Significant univariable predictors of chronic anxiety were type-D personality (OR: 3.17; 95% CI: 1.64-6.14) and sirolimus-eluting stent implantation (OR: 0.51; 95% CI: 0.27-0.98), with sirolimus-eluting stent showing a protective effect. In multivariable analyses, type-D personality (OR: 3.31; 95% CI: 1.59-6.87) and sirolimus-eluting stent implantation (OR: 0.44; 95% CI: 0.21-0.92) remained significant independent predictors of chronic anxiety adjusting for depressive symptoms at 6 months, demographic and clinical risk factors. Limitations: All psychological measures were based on self-report, and we had no information on cardiac rehabilitation or use of pharmacotherapy; however our sample represented patients seen in daily clinical practice. Conclusions: These findings suggest that type-D personality is a risk factor and sirolimus-eluting stent implantation a protective factor ...