Residents living nearby multiple sources of environmental pollution are suffering from adverse health effects and many other factors. However, very few studies focus on the complex interaction between multiple effects on residents' satisfaction. This study reports a case study in Phuoc Tuong quarry and Khanh Son landfill in Danang city, Vietnam, the two environmental hotspots hindering city development toward sustainability. Using Structural Equation Modelling (SEM) approach and 420 valid questionnaires, the relationship between measured variables and latent constructs was analyzed and established. Due to the wider spread of influencing area, the effects of Phuoc Tuong quarry are higher than Khanh Son landfill (path coefficient |ß| = 0.265 > 0.161), whereas, living distance (ß = 0.165) and residents' demographics (|ß| = 0.134) are also contributing to residents' satisfaction with business, health and life in overall. Among them, living distance from the pollution sources is confirmed to have a positive influence while the rest constructs negatively influence residents' satisfaction. The satisfaction, in turn, has a direct negative influence on residents' moving intention, meaning residents desire to resettle their living locations when dissatisfied with the current living conditions. Based on the study findings, practical applications can be focused more efficiently on appropriate measures to reduce the harmful effects of the quarry as compared to the landfill. Also, urgent measures should also be focused on the resident group living within 1 km from both pollution sources.