The preference for walking and the resulting pedestrian activities have been considered key success factors for streets, neighborhoods, and cities alike. Although micro- and meso-scale built environment factors that encourage walking have been investigated, the role of macroscopic factors such as regional centrality in explaining street-level pedestrian volume is often neglected. Against this backdrop, this study examines the relationship between built environments and street-level pedestrian volume using Smart Card and pedestrian volume survey data from Seoul after controlling for transport ridership as a proxy for regional centrality. As a preliminary study, we analyzed 36 regression models applying different sets of transit ridership variables and found that the combination of bus ridership within 400 m and subway ridership within 300 m best explained the variation in pedestrian volume on a street. Then, the effects of the 3D variables (density, diversity, and design) on pedestrian volume were compared before and after controlling for ridership within this spatial range. The results demonstrated that, after taking transit ridership into account, the influence of built environment variables is generally reduced, and the decrease is more pronounced among walkshed-level 3D variables than street-level variables. Particularly, while the effect of “design” (street connectivity) on pedestrian volume appeared to be negatively significant in the constrained model, it was found to be insignificant in the unconstrained model which controlled for transit ridership. This suggests that the degree of street connectivity is influenced by regional centrality, and accordingly, the coefficient of the “design” variable in our constrained model might be biased. Thus, to accurately understand the effect of the meso-scale 3D variables on pedestrian volume, both micro- and macro-scale built environmental factors should be controlled.