Background: Prevalence and predictors of perinatal mental health are understudied in majority world contexts. The present study investigated a range of co-occurring perinatal mood conditions (depression, perceived stress, and pregnancy anxiety) in a rural area of The Gambia, West Africa. The aims were to adapt self-report measures for use in this setting, and then to use the adapted tool to examine relevant socioeconomic (SES) and health-related predictors. Methods: Participants included N=205 women in their third trimester of pregnancy who were taking part in the Brain Imaging for Global Health (BRIGHT) project. Mental health was reported by women using the Edinburgh Postnatal Depression Scale (EPDS), Perceived Stress Scale (PSS), Pregnancy Specific Anxiety Scale (PSA), and Pregnancy Related Anxiety Scale (PRAS). The measures were adapted for the Mandinka language, with necessary contextual adaptations. SES and health factors included maternal age, parity, educational attainment, income, occupation, household size, and anaemia. Results: Participants reported low levels of distress or inability to cope. Measures varied in their utility; the PRAS had the highest internal consistency (IC) and showed associations with predicted SES factors. All measures were significantly correlated with each other. Lower income, being a farmer, and greater household size predicted higher anxiety and stress, while none of the factors predicted depression.Conclusion: Overall, pregnant women in this setting to did not report heightened mental health difficulties. However, poverty-related factors contributed to greater stress and anxiety. We highlight the importance of examining multiple, overlapping conditions and a wider range of predictors in diverse contexts.