Percentile-based assessment of craniosynostosis

Wilbrand, Jan-Falco; Bierther, Uta; Nord, Thomas; Reinges, M. H. T.; Hahn, Andreas; Christophis, P.; Streckbein, Philipp; Kähling, Christopher; Howaldt, Hans‐Peter

doi:10.1016/j.jcms.2013.09.005

Cited by 17 publications

(18 citation statements)

References 35 publications

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“…Beckett et al 2 found that the endocranial bifrontal angle varied significantly between patients with trigonocephaly and controls, and defined 2 severity grades. Wilbrand and colleagues 20 described their percentile-based assessment of craniosynostosis, comparing values obtained in patients against normative values for cranial circumference, length, and width, cranial index, as well as sagittal and transversal circumference. Our goal was to describe an anthropomorphic index that would afford similar reliability and would allow for rapid calculation from both CT scans and clinical examination using values obtained with measuring calipers.…”

Section: Discussionmentioning

confidence: 99%

The metopic index: an anthropometric index for the quantitative assessment of trigonocephaly from metopic synostosis

Wang¹,

Dorafshar

Liu³

et al. 2016

PED

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OBJECTIVE Because the metopic suture normally fuses during infancy, there are varying degrees of severity in head shape abnormalities associated with premature fusion. A method for the objective and reproducible assessment of metopic synostosis is needed to guide management, as current methods are limited by their reliance on aesthetic markers. The object of this study was to describe the metopic index (MI), a simple anthropometric cranial measurement. The measurements can be obtained from CT scans and, more importantly, from palpable cranial landmarks, and the index provides a rapid tool for evaluating patients in both pre- and postoperative settings. METHODS High-resolution head CT scans obtained in 69 patients (age range 0–24 months) diagnosed with metopic craniosynostosis were retrospectively reviewed. Preoperative 3D reconstructions were available in 15 cases, and these were compared with 3D reconstructions of 324 CT scans obtained in a control group of 316 infants (age range 0–24 months) who did not have any condition that might affect head size or shape and also in a subset of this group, comprising 112 patients precisely matched to the craniosynostosis patients with respect to age and sex. Postoperative scans were available and reviewed in 9 of the craniosynostosis patients at a mean time of 7.1 months after surgical repair. 3D reconstructions of these scans were matched with controls based upon age and sex. RESULTS The mean preoperative MI for patients with trigonocephaly was 0.48 (SD 0.05), significantly lower than the mean values of 0.57 (SD 0.04) calculated on the basis of all 324 scans obtained in controls (p < 0.001) and 0.58 (SD 0.04) for the subset of 112 age- and sex-matched controls (p < 0.001). For 7 patients with both pre- and postoperative CT scans available for evaluation, the mean postoperative MI was 0.55 (SD 0.03), significantly greater than their preoperative MIs (mean 0.48 [SD 0.04], p = 0.001) and comparable to the mean MI of the controls (p = 0.30). In 4 patients, clinically obtained postoperative MIs by caliper measurement were comparable to measurements derived from CT (p = 0.141). CONCLUSIONS The MI is a useful measurement of the severity of trigonocephaly in patients with metopic synostosis. This simple quantitative assessment can potentially be used in the clinical setting to guide preoperative evaluation, surgical repair, and postoperative degree of correction.

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Section: Discussionmentioning

confidence: 99%

The metopic index: an anthropometric index for the quantitative assessment of trigonocephaly from metopic synostosis

Wang¹,

Dorafshar

Liu³

et al. 2016

PED

View full text Add to dashboard Cite

show abstract

“…Wilbrand et al [25] confirmed that most children with sagittal synostosis were above the 90th percentile for cranial circumference and length, whereas only 27.9% were below the 10th percentile for cranial width.…”

Section: Discussionmentioning

confidence: 96%

“…For trigonocephaly, Wilbrand et al [25] found normal cranial circumference values in most patients (10th-90th percentile), 40.9% were above the 90th percentile for cranial length and 63.1% and 57.9% were above the 90th percentiles for sagittal and transverse circumferences.…”

Section: Discussionmentioning

confidence: 98%

“…Wilbrand et al [25] found that most (83%) children with scaphocephaly had cranial indices below the 10th percentile.…”

Section: Discussionmentioning

confidence: 99%

“…Wilbrand et al [25] evaluated anthropometric data via percentile based assessment of CS. They focused to find an objective method to assess cranial deformation based on normative craniofacial percentiles.…”

Section: Discussionmentioning

confidence: 99%

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