Perception is deceiving; the real gender specific exercise capacity of heart transplant recipients

Cole, Brandi; Kobashigawa, J.A.; Patel, Jay; Moriguchi, J.; Vassilakis, Maria Espejo; Go, S. E.; Chait, J.; Laks, Hillel

doi:10.1016/s1053-2498(02)01146-4

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“…Cole et al [9] recently found that female cardiac transplant recipients' aerobic capacity was 60% lower than age-predicted values. Consistent with this finding, our transplant recipients' baseline aerobic endurance was 50% lower than age predicted values.…”

Section: Discussionmentioning

confidence: 99%

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Exercise training improves aerobic endurance and musculoskeletal fitness in female cardiac transplant recipients

Haykowsky

Riess

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et al. 2005

Trials

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Aim: Female cardiac transplant recipients' aerobic capacity is 60% lower than sex and agepredicted values. The effect of exercise training on restoring the impaired aerobic endurance and muscle strength in female cardiac transplant recipients is not known. This study examined the effect that aerobic and strength training have on improving aerobic endurance and muscle strength in female cardiac transplant recipients.Methods: 20 female cardiac transplant recipients (51 ± 11 years) participated in this investigation. The subjects performed a baseline six-minute walk test and a leg-press strength test when they were discharged following cardiac transplantation. The subjects then participated in a 12-week exercise program consisting of aerobic and lower extremity strength training. Baseline assessments were repeated following completion of the exercise intervention.Results: At baseline, the cardiac transplant recipients' aerobic endurance was 50% lower than agematched predicted values. The training program resulted in a significant increase in aerobic endurance (pre-training: 322 ± 104 m vs. post-training: 501 ± 99 m, p < 0.05) and leg-press strength (pre-training: 48 ± 16 kg. vs. post-training: 78 ± 27 kg, p < 0.05). Conclusion:Aerobic and strength training are effective interventions that can partially restore the impaired aerobic endurance and strength found in female cardiac transplant recipients.Exercise training is an effective intervention that can partially restore the impaired aerobic capacity and musculoskeletal fitness (i.e. muscle strength) found in cardiac transplant recipients [1,2]. However, previous reports have focused exclusively on the effects of exercise training in men. Therefore, the effect of exercise training on these outcomes in female cardiac transplant recipients is not known [2][3][4][5][6][7]. Importantly, a majority of female cardiac transplant recipients do not engage in regular physical activity leading to increased levels of fatigue, poor functional status and reduced exercise capacity [8][9][10]. Based on this rationale, the aim of this study is to examine the effect that exercise training has on improving aerobic endurance (i.e. distance walked in six-minutes) and lower extremity muscle strength in female cardiac transplant recipients. We hypothesized that exercise training would be a feasible and effective intervention to improve aerobic endurance and lower extremity strength in female cardiac transplant recipients. Methods Subjects and proceduresThe participants for this study consisted of 20 (51 ± 11 years) clinically stable female cardiac transplant recipients who participated in the University of Alberta Post-Transplant Exercise Rehabilitation program between 1997 and 2003. All assessments and exercise training were performed in the Physical Therapy Department at the University of Alberta Hospital. Ethics approval for this study was obtained from the Biomedical Ethics Board at our University. Outcome AssessmentsThe six-minute walk test was performed in accordance with t...

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Section: Discussionmentioning

confidence: 99%

“…A majority of female cardiac transplant recipients adhere to a sedentary lifestyle and as result their aerobic capacity is 60% lower than age-predicted values [9]. The effect that exercise training has on improving female cardiac transplant recipients' aerobic endurance and lower extremity strength is not known.…”

Section: Discussionmentioning

confidence: 99%