“…Based on these findings, and those from subsequent studies, clinical practice guidelines from multiple professional societies, including the Society for Critical Care Medicine, have recommended that patients with critical illness be physically active early and often seems a straightforward directive (5–7). Nevertheless, implementation of these interventions in clinical practice remains low (8). Although this may simply reflect the well-described delay between research findings and clinical practice, it may also reflect the fact that findings from the largest of these trials are mixed (4, 9–13).…”