2020
DOI: 10.1186/s41687-020-0179-1
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Perception of quality of life in people experiencing or having experienced a Clostridioides difficile infection: a US population survey

Abstract: Background: Although the incidence, severity and mortality of Clostridioides (Clostridium) difficile infection (CDI) have been increasing, patients' quality of life changes resulting from CDI have not been studied thoroughly. This study aimed at exploring the consequences of CDI on quality of life through patients' perspective. Methods: An observational, cross-sectional study involving 350 participants with a self-reported CDI diagnosis was conducted through an online self-administered survey. Participants wer… Show more

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Cited by 40 publications
(59 citation statements)
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“…Data indicates that co-pays of Medicare patients, a high-risk group for primary and recurrent CDI, often exceeds USD 10,000 [11]. Data also indicates that HCA-CDI has considerable physical and psychologic consequences on patients and limits their ability to return to work and resume normal daily activities [50]. Finally, the model was limited to the excess costs associated with HCA-CDI and did not include other important consequences associated with reduction of third generation cephalosporins and fluroquinolones use, such as the reduction of extended spectrum beta-lactamase producing Gram-negatives and MRSA rates [51].…”
Section: Discussionmentioning
confidence: 99%
“…Data indicates that co-pays of Medicare patients, a high-risk group for primary and recurrent CDI, often exceeds USD 10,000 [11]. Data also indicates that HCA-CDI has considerable physical and psychologic consequences on patients and limits their ability to return to work and resume normal daily activities [50]. Finally, the model was limited to the excess costs associated with HCA-CDI and did not include other important consequences associated with reduction of third generation cephalosporins and fluroquinolones use, such as the reduction of extended spectrum beta-lactamase producing Gram-negatives and MRSA rates [51].…”
Section: Discussionmentioning
confidence: 99%
“… 9 – 11 The presence of diarrhoea may affect the patients’ ability to perform their usual activities and have adverse social impacts. 10 , 11 In addition, emotional distress can present as a consequence of the disease, 10 , 11 and most patients fear worsening of symptoms and recurrence of CDI. 10 Studies indicate that these impacts may persist even after receiving effective treatment.…”
Section: Introductionmentioning
confidence: 99%
“… 10 , 11 In addition, emotional distress can present as a consequence of the disease, 10 , 11 and most patients fear worsening of symptoms and recurrence of CDI. 10 Studies indicate that these impacts may persist even after receiving effective treatment. 10 , 11 …”
Section: Introductionmentioning
confidence: 99%
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“…6,7 Patients with C difficile infection unfortunately develop several psychosocial complications including anxiety of illness and a decreased quality of life. 8 Although it has been known for more than 4 decades that this bacterium causes human diarrhea, there remain several challenges to make an accurate diagnosis and optimal management of C difficile infection. 2 When this bacterium was first discovered, it was named a "difficult" Clostridium because of the difficulty of culturing this bacterium; this holds true more than 80 years later due to the difficulty in its management.…”
mentioning
confidence: 99%