Perceptions of Financial Payment for Research Participation among African-American Drug Users in HIV Studies

Slomka, Jacquelyn; McCurdy, Sheryl A.; Ratliff, Eric A.; Timpson, Sandra C.; Williams, Mark L.

doi:10.1007/s11606-007-0319-9

Cited by 76 publications

(90 citation statements)

References 35 publications

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“…Using standard qualitative interview techniques (Patton, 2002), we conducted 41 semistructured, open-ended, in-depth interviews as a pilot study of economically disadvantaged African-American crack cocaine smokers' motivations to participate in research (Slomka, McCurdy, Ratliff, Timpson, & Williams, 2007;Slomka, Ratliff, McCurdy, Timpson, & Williams, 2008). Data were obtained from 37 usable interviews.…”

Section: Design Setting and Populationmentioning

confidence: 99%

“…Interviews were conducted from February to May 2006, at a research field office established for the parent projects in two underserved urban communities in Houston, Texas. Participant characteristics are reported elsewhere (Slomka et al, 2007) and summarized in Table 1. This study was approved by the University of Texas Health Science Center's Committee for the Protection of Human Subjects.…”

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confidence: 99%

“…These scenarios were typical of research studies in which individuals with or at risk for HIV might be asked to participate. As a means of eliciting differences in participants' perception of risk and benefit between and among clinical studies, the scenarios described elsewhere (Slomka et al, 2007) and described in Table 2, were designed to represent different levels of risk. The scenarios included a survey study relating sleep disturbances and stress (minimal risk); a randomized, controlled trial of a new medication (more than minimal risk); and a test of a vaccine for HIV (more than minimal risk).…”

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confidence: 99%

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Perceptions of Risk in Research Participation Among Underserved Minority Drug Users

Slomka

Ratliff

McCurdy

et al. 2008

Substance Use & Misuse

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Research with underserved minority drug users is essential to quality health care and prevention. Understanding how participants perceive risk in research is necessary to inform research regulators so that research protections are neither lax, exposing participants to harm, nor overly stringent, thereby denying access to beneficial research. Data from 37 semistructured interviews of underserved, African-American crack cocaine users, collected from February to May 2006 in a large, urban setting, were analyzed using content analysis. In three hypothetical studies, participants recognized risks as relative and articulated and evaluated specific risks. Research regulators may enhance the accuracy of risk assessment in research by incorporating the views of participants. Study implications and limitations are noted. Future research on risk perception in research participation is suggested.Keywords risk perception; drug use; HIV/AIDS; research ethics; underserved minorities; research participation; research risk Access to preventive health measures and treatment is essential for drug users with or who are at risk for HIV/AIDS. But simply ensuring access is not enough: Prevention and treatment must be high quality, based on rigorous research evidence. Weighing the risks and benefits of research participation is standard practice in all research, but especially so in research with "vulnerable" participants such as drug users and minority populations. Understanding how participants perceive risk in research is necessary to inform research regulators so that research protections are neither lax, exposing participants to harm, nor overly stringent, thereby denying access to beneficial research (Mastroianni and Kahn, 2001). Although all health research conducted in the United States is assessed for proportional risks and benefits by Institutional Review Boards (IRBs), little is known about whether and/or how underserved minority drug users at risk for HIV perceive risks associated with research participation. The question of risk in research is important because minority populations are underrepresented in research and may have difficulty gaining access to experimental treatments for HIV infection (Gifford et al., 2002). If IRBs and other research regulators require protections based on an assumption of risk disproportional to the actual situation, they may inadvertently work to deny underserved minorities the benefits of access to HIV and substance abuse research.The use of illicit drugs exposes users to a variety of risks related to harm. How such risks are recognized and defined is pertinent to individual, research, and policy efforts to decrease risk. NIH-PA Author ManuscriptNIH-PA Author Manuscript NIH-PA Author ManuscriptEpidemiologists view risk as an objective and quantifiable phenomenon. On the other hand, social scientists have argued that risk cannot be measured as an absolute value. Rather, perceptions of risk are formulated through social processes in which individuals and communities engage. The defin...

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Section: Design Setting and Populationmentioning

confidence: 99%

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confidence: 99%

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confidence: 99%

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Perceptions of Risk in Research Participation Among Underserved Minority Drug Users

Slomka

Ratliff

McCurdy

et al. 2008

Substance Use & Misuse

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“…Likewise, Aschcroft 9 indicated that the payment affects the quality of the informed consent and represents a circumstance that is favorable to the exploitation of the participant. As reported by Slomka and others 10 , in the USA, it is normal to offer payment in order to recruit individuals to participate in studies. However, questions related to its conception, methods and the amount to be paid remain controversial.…”

Section: Payment Of Participants In Clinical Studies: Current Panoramamentioning

confidence: 99%

Remuneração dos participantes de pesquisas clínicas: considerações à luz da Constituição

Albuquerque

Barboza

2016

Rev. Bioét.

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Resumo Remuneração dos participantes de pesquisas clínicas: considerações à luz da ConstituiçãoA Resolução CNS 466/2012 do Ministério da Saúde estabelece a possibilidade de se ofertar quantia financeira a participante de pesquisas clínicas de fase I ou de bioequivalência, e a Constituição Federal de 1988 assenta a vedação absoluta de comercialização do corpo humano. Esta pesquisa, de cunho ético-jurídico, analisa a participação não gratuita de indivíduos em pesquisa à luz do tratamento teórico internacional do tema e do arcabouço constitucional brasileiro. Conclui que não há consenso no mundo acerca do que seja pagamento que caracterize "indução indevida", mormente quando se considera que há pessoas que vivem à margem da linha de pobreza, o que, particularmente no Brasil, é um problema crucial. Tendo em conta a vedação constitucional de qualquer tipo de comercialização do corpo humano, este texto sustenta a inadequação ética e legal do dispositivo da Resolução CNS 466/2012. Palavras-chave: Pesquisa. Remuneração. Resolução 466/2012. Constituição federal. ResumenRemuneración de los participantes de investigaciones clínicas: consideraciones a la luz de la Constitución La Resolución CNS 466/2012 establece la posibilidad de ofrecer una cuantía financiera a los participantes de investigaciones clínicas de Fase I o de bioequivalencia y, la Constitución Federal de 1988 determina la prohibición absoluta de la comercialización del cuerpo humano. Esta investigación de naturaleza ético-jurídica, analiza la participación no gratuita de los individuos en investigaciones a la luz del tratamiento teórico internacional del tema y del marco constitucional brasilero. Se concluyó que no existe un consenso internacional acerca de lo que es un pago que caracterice el "incentivo indebido", principalmente si tenemos en cuenta que hay personas que viven en el margen de la línea de pobreza, lo cual se exhibe particularmente en Brasil como un problema importante. Teniendo en cuenta la prohibición constitucional de todo tipo de comercialización del cuerpo humano, este texto es compatible con la insuficiencia ética y legal del dispositivo de la Resolución CNS 466/2012. Palabras-clave: Investigación. Remuneración. Resolución 466/2012. Constitución federal.

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“…Concerns about participants using monetary incentives to purchase drugs may be even more heightened in contemporary Western societies that place a moral imperative on health-promoting activities and condemn actions destructive to one’s health (Katz, 1997). Empirical examination of these concerns have found that while drug users often cite monetary incentives as a primary reason for participation in research studies on drug use and HIV (Grady et al, 2008; Jenkins et al, 2000; Slomka, McCurdy, Ratliff, Timpson, and Willams, 2007), they also cite opportunity to gain personal and health-related knowledge, material goods for family members, or to contribute to scientific knowledge and policy (Barratt et al, 2007; Fry and Dwyer, 2001; Sherman and Latkin, 1999; Wright, Klee, and Reid, 1998). Recently, Festinger and fellow researchers (2005) found that while increasing amounts of monetary incentives were effective in preventing study attrition among drug using participants, they neither led to increased drug use nor higher rates of self-reported coercion.…”

Section: Introductionmentioning

confidence: 99%

Barriers and Opportunities for Recruitment for Nonintervention Studies on HIV Risk: Perspectives of Street Drug Users

Oransky

Fisher²,

Mahadevan³

et al. 2009

Substance Use & Misuse

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This study used focus-group discussions in response to a video vignette to examine attitudes toward recruitment for nonintervention research involving HIV testing. Participants were 100 ethnically diverse, economically disadvantaged urban drug users, who were recruited from New York City and Hartford, Connecticut in the spring and summer of 2006. Content analyses revealed themes including (1) fears of stigma and legal trouble balanced by trustworthiness of the recruiter; (2) fears of learning one’s HIV status balanced by prospects for health benefits, and (3) the right to receive fair monetary compensation balanced by risks of coercion during periods of cravings. Limitations and implications for recruitment practices have been discussed here.

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Perceptions of Financial Payment for Research Participation among African-American Drug Users in HIV Studies

Cited by 76 publications

References 35 publications

Perceptions of Risk in Research Participation Among Underserved Minority Drug Users

Perceptions of Risk in Research Participation Among Underserved Minority Drug Users

Remuneração dos participantes de pesquisas clínicas: considerações à luz da Constituição

Barriers and Opportunities for Recruitment for Nonintervention Studies on HIV Risk: Perspectives of Street Drug Users

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